BAG1 protein, human

Known as: BAG1, BCL2-associated athanogene 1 protein, human, BAG1 Protein 
Encoded by human BAG1 Gene as isoforms 1 (274-aa, 31-kD) and 2 (240-aa), acidic (pI 5.3) glutamate-rich BAG1 Protein contains a Ubiquitin-like domain… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a… (More)
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Highly Cited
2011
Highly Cited
2011
Dilated cardiomyopathy commonly causes heart failure and is the most frequent precipitating cause of heart transplantation… (More)
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2011
2011
Aberrant methylation has been shown to trigger the inactivation of tumor suppressor genes during tumorigenesis. MicroRNAs (miRNAs… (More)
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2011
2011
There is a reciprocal change in the expression of two members of the BAG (Bcl-2-associated athanogen) family, BAG1 and BAG3… (More)
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Highly Cited
2009
Highly Cited
2009
The Hsc/Hsp70 co-chaperones of the BAG (Bcl-2-associated athanogene) protein family are modulators of protein quality control. We… (More)
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Highly Cited
2009
Highly Cited
2009
Autophagy is an intracellular process in which a cell digests its own constituents via lysosomal degradative pathway. Though… (More)
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Highly Cited
2005
Highly Cited
2005
Bag1 is a cochaperone for the heat-shock protein Hsp70 that interacts with C-Raf, B-Raf, Akt, Bcl-2, steroid hormone receptors… (More)
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Highly Cited
2001
Highly Cited
2001
Survival after stress requires the precise orchestration of cell-signalling events to ensure that biosynthetic processes are… (More)
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Highly Cited
2001
Highly Cited
2001
BAG-family proteins share a conserved protein interaction region, called the 'BAG domain', which binds and regulates Hsp70/Hsc70… (More)
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1996
1996
cDNAs encoding the human homolog of BAG1, a Bcl-2-binding protein with anti-apoptotic function, were cloned. DNA sequence… (More)
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