BAD gene

Known as: BCL2-BINDING PROTEIN, BCL2 associated agonist of cell death, BCL2-Associated Agonist of Cell Death Gene 
The gene plays a role in the positive regulation of cellular apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0102019752017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Tumor cells with mutated PTEN proliferate in an EGFR-independent manner. Induction of PTEN sensitizes cells to EGFR inhibition… (More)
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Highly Cited
2004
Highly Cited
2004
The phosphatidylinositol 3-kinase (PI3K)/AKT protein kinase pathway is involved in cell growth, proliferation, and apoptosis. The… (More)
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Highly Cited
2003
Highly Cited
2003
BAD, a proapoptotic molecule of the BCL2 family, is regulated by reversible phosphorylation. During survival, BAD is sequestered… (More)
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Highly Cited
2003
Highly Cited
2003
Neuronal apoptosis has been implicated as an important mechanism of cell death in acute and chronic neurodegenerative disorders… (More)
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Highly Cited
2002
Highly Cited
2002
A mechanism that triggers neuronal apoptosis has been characterized. We report that the cell cycle-regulated protein kinase Cdc2… (More)
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Highly Cited
2002
Highly Cited
2002
The c-Jun N-terminal kinase (JNK) signaling pathway plays a critical role in mediating apoptosis in the developing and mature… (More)
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Highly Cited
2000
Highly Cited
2000
The Bcl-2 family protein BAD promotes apoptosis by binding through its BH3 domain to Bcl-x(L) and related cell death suppressors… (More)
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Highly Cited
2000
Highly Cited
2000
This study, for the first time, distinguishes between nightmares and bad dreams, measures the frequency of each using dream logs… (More)
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Highly Cited
1999
Highly Cited
1999
The Ca2+-activated protein phosphatase calcineurin induces apoptosis, but the mechanism is unknown. Calcineurin was found to… (More)
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Highly Cited
1998
Highly Cited
1998
Prior investigations document that proliferative signaling cascades, under some circumstances, initiate apoptosis, although… (More)
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