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Azurophil granule

Known as: primary granule 
Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The elaboration of dendrites is fundamental to the establishment of neuronal polarity and connectivity, but the mechanisms that… Expand
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Highly Cited
2004
Highly Cited
2004
The mouse has become an important model for immunological studies including innate immunity. Creating transgenic mice offers… Expand
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Highly Cited
2002
Highly Cited
2002
The c-Jun N-terminal kinase (JNK) signaling pathway plays a critical role in mediating apoptosis in the developing and mature… Expand
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Highly Cited
2001
Highly Cited
2001
Initially identified in high-grade gliomas, mutations in the PTEN tumor-suppressor are also found in many sporadic cancers and a… Expand
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Highly Cited
2001
Highly Cited
2001
Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. The known biologic… Expand
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Highly Cited
1997
Highly Cited
1997
A direct, rapid, quantitative colorimetric assay to determine neutrophil primary granule degranulation was adapted for use with… Expand
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Highly Cited
1994
Highly Cited
1994
The presence of anti-neutrophil cytoplasmic Abs (ANCA) in many patients with systemic vasculitis suggests that ANCA may play a… Expand
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Highly Cited
1991
Highly Cited
1991
Polymorphonuclear leukocyte (PMN) respiratory burst was stimulated by heterologous antibodies against PMN granule proteins but… Expand
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Highly Cited
1990
Highly Cited
1990
Anti-neutrophil cytoplasmic autoantibodies (ANCA) are in the circulation of most patients with pauci-immune necrotizing… Expand
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Highly Cited
1989
Highly Cited
1989
The cytokine interleukin 6 (IL-6) has been shown to have multiple biological activities against many cellular targets. The… Expand
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