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Autologous HNSCC DNA-transfected Semi-allogeneic Fibroblasts MRC-5 Vaccine

A vaccine consisting of lethally irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous tumor DNA… Expand
National Institutes of Health

Papers overview

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2014
2014
Cisplatin-based chemotherapy is the standard treatment of choice for head and neck squamous cell carcinoma (HNSCC). The… Expand
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Highly Cited
2012
Highly Cited
2012
BackgroundHuman papillomavirus-positive (HPV+) head and neck squamous cell carcinoma (HNSCC) represents a distinct clinical and… Expand
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Highly Cited
2011
Highly Cited
2011
MicroRNA-200c (miR200c) is emerging as an important regulator of tumourigenicity and cancer metastasis with a strong capacity for… Expand
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Highly Cited
2011
Highly Cited
2011
Recent studies suggest that ALDH1 is a putative marker for HNSCC-derived cancer stem cells. However, the regulation mechanisms… Expand
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Highly Cited
2010
Highly Cited
2010
Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer worldwide. Signal transducers and activators of transcription… Expand
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Highly Cited
2010
Highly Cited
2010
Bmi-1, a member of the Polycomb family of transcriptional repressors, is essential for maintaining the self-renewal abilities of… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND To investigate whether human papilloma virus (HPV)-specific immune mechanisms can result in tumor clearance, we have… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND High-risk types of human papillomavirus (HPV), including HPV-16, cause a subgroup of head and neck squamous cell… Expand
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Highly Cited
2008
Highly Cited
2008
We assessed the immunological status of stage III and IV head and neck squamous cell carcinoma (HNSCC) patients and age-matched… Expand
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2008
2008
Purpose: Oral human papillomavirus (HPV) infection is a risk factor for head and neck squamous cell carcinoma (HNSCC), and is a… Expand
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