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Attenuated Live Listeria Encoding HPV 16 E7 Vaccine ADXS11-001

Known as: Lovaxin-C, ADXS11-001 Vaccine, Attenuated Live Listeria Encoding HPV 16 E7 Vaccine 
A cancer vaccine containing a live-attenuated strain of the bacterium Listeria monocytogenes (Lm) encoding human papillomavirus (HPV) type 16 E7… Expand
National Institutes of Health

Papers overview

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2018
2018
Objectives A global unmet medical need exists for effective treatments for persistent, recurrent, or metastatic cervical cancer… Expand
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Review
2014
Review
2014
Listeria monocytogenes is a bacterium that can be genetically modified to express fusion proteins with antigens specific to… Expand
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2014
2014
5610 Background: ADXS11-001 immunotherapy is a live attenuated Listeria monocytogenes (Lm) bioengineered to secrete a HPV-16-E7… Expand
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2014
2014
Studies have shown that Listeria monocytogenes (Lm)-based vaccine expressing a fusion protein comprising truncated listeriolysin… Expand
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2013
2013
BackgroundOne of the significant tumor immune escape mechanisms and substantial barrier for successful immunotherapy is tumor… Expand
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2012
2012
HPV infection is a direct cause of neoplasia and malignancy. Cellular immunologic activity against cells expressing HPV E6 and E7… Expand
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Highly Cited
2009
Highly Cited
2009
Invasive carcinoma of the cervix (ICC) is the second most common cancer in women worldwide. Lm-LLO-E7 vaccine is a live… Expand
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2009
2009
Producing effective therapeutic vaccines has proved much more difficult and challenging than developing cancer preventive… Expand
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2004
2004
Previous work from our laboratory has shown that Lm-LLO-E7 induces complete regression of approximately 75% of established TC-1… Expand
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Highly Cited
2001
Highly Cited
2001
Two recombinant Listeria monocytogenes (rLm) strains were produced that secrete the human papilloma virus-16 (HPV-16) E7 protein… Expand
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