Astrotactin-2

Astrotactin-2 (1339 aa, ~148 kDa) is encoded by the human ASTN2 gene. This protein may play a role in neuronal development.
National Institutes of Health

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ASTN2 geneGenes, RegulatorNeurogenesisSchizophrenia

Papers overview

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2018
2018
Induced pluripotent stem cells derived from a schizophrenia patient with ASTN2 deletion.
Astrotactin-2, encoded by ASTN2, is implicated in neuronal migration. Although genetic studies of schizophrenia (SCZ) patients… (More)
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2016
2016
Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development
The vertebrate-specific proteins astrotactin-1 and 2 (ASTN-1 and ASTN-2) are integral membrane perforin-like proteins known to… (More)
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2016
2016
Disruption of human astn 2 function by ZIKV ns 4 b gene as a molecular basis for Zika viral microcephaly
The present Zika virus (ZIKV) pandemic is being associated with increased incidence of microcephaly in newborns. However, a… (More)
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2015
2015
Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles
Planar cell polarity (PCP) signaling controls the global orientation of surface structures, such as hairs and bristles, in both… (More)
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