FAQ

Aspartylglucosylaminase

Known as: Amidohydrolase, Aspartylglucosamine, N(4)-(beta-N-Acetyl-D-glucosaminyl)-L-asparagine amidohydrolase, Deaspartylase, Aspartylglucosylamine 
An enzyme that catalyzes the conversion of N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine and water to N-acetyl-beta-D-glucosaminylamine and L… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2017
02419832017

Related topics

Related topics

11 relations
AGA geneAspartylglucosaminuriaIn BloodProcess of secretion
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Aspartylglucosylaminase
physiological aspects
chemical synthesis
Aspartylglucosaminuria
standards characteristics
Process of secretion

Papers overview

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2010
2010
Crystallographic snapshot of glycosylasparaginase precursor poised for autoprocessing.
Glycosylasparaginase belongs to a family of N-terminal nucleophile hydrolases that autoproteolytically generate their mature… (More)
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2009
2009
Reduced-intensity allogeneic transplantation combined with imatinib mesylate for chronic myeloid leukemia in first chronic phase
specificity and reaction mechanism of human glycosylasparaginase. The N-glycosidic linkage of various glycoasparagines is cleaved… (More)
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2004
2004
Autoproteolytic activation of human aspartylglucosaminidase.
Aspartylglucosaminidase (AGA) belongs to the N-terminal nucleophile (Ntn) hydrolase superfamily characterized by an N-terminal… (More)
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2003
2003
Two-step dimerization for autoproteolysis to activate glycosylasparaginase.
Glycosylasparaginase (GA) is an amidase and belongs to a novel family of N-terminal nucleophile hydrolases that use a similar… (More)
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2003
2003
A dual role for an aspartic acid in glycosylasparaginase autoproteolysis.
Glycosylasparaginase uses an autoproteolytic processing mechanism, through an N-O acyl shift, to generate a mature/active enzyme… (More)
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1998
1998
Characterization and functional analysis of the cis-autoproteolysis active center of glycosylasparaginase.
Glycosylasparaginase is an N-terminal nucleophile hydrolase and is activated by intramolecular autoproteolytic processing. This… (More)
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1998
1998
Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis.
Glycosylasparaginase (GA) is a member of a novel family of N-terminal nucleophile hydrolases that catalytically use an N-terminal… (More)
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1998
1998
Glycosylasparaginase-catalyzed synthesis and hydrolysis of beta-aspartyl peptides.
beta-Aspartyl di- and tripeptides are common constituents of mammalian metabolism, but their formation and catabolism are not… (More)
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Highly Cited
1996
Highly Cited
1996
Searching databases of conserved sequence regions by aligning protein multiple-alignments.
A general searching method for comparing multiple sequence alignments was developed to detect sequence relationships between… (More)
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1996
1996
Purification, biochemistry and molecular cloning of an insect glycosylasparaginase from Spodoptera frugiperda.
Glycosylasparaginase (EC 3.5.1.26) from Sf9 cells (Spodoptera frugiperda) was purified to homogeneity with a specific activity of… (More)
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