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Asialoglycoprotein Receptor

Known as: Receptor, Asialoglycoprotein, ASGP-R, Asialoorosomucoid Receptors 
A C-type lectin that is a cell surface receptor for ASIALOGLYCOPROTEINS. It is found primarily in the LIVER where it mediates the endocytosis of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Although surface sialic acid is considered a key determinant for the survival of circulating blood cells and glycoproteins, its… Expand
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Highly Cited
2005
Highly Cited
2005
Hepatic transdifferentiation of bone marrow cells has been previously demonstrated by intravenous administration of donor cells… Expand
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Highly Cited
2005
Highly Cited
2005
Endogenous ligands have not, to date, been identified for the asialoglycoprotein receptor (ASGP-R), which is abundantly expressed… Expand
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Highly Cited
2002
Highly Cited
2002
A number of poorly characterized genetic modifiers contribute to the extensive variability of von Willebrand disease, the most… Expand
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Review
2002
Review
2002
Animal cells internalize specific extracellular macromolecules (ligands) by using specialized cell surface receptors that operate… Expand
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Highly Cited
2001
Highly Cited
2001
The asialoglycoprotein receptor (ASGPr) on hepatocytes plays a role in the clearance of desialylated proteins from the serum… Expand
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Highly Cited
1992
Highly Cited
1992
We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a… Expand
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Review
1990
Review
1990
 
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Highly Cited
1988
Highly Cited
1988
  • G. Wu, C. Wu
  • The Journal of biological chemistry
  • 1988
  • Corpus ID: 19163151
A soluble DNA carrier system was used to target a foreign gene specifically to liver in vivo via asialoglycoprotein receptors… Expand
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Highly Cited
1983
Highly Cited
1983
In rats infused with asialoglycoprotein for 60 min, receptor-mediated endocytosis of the ligand occurred exclusively in hepatic… Expand
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