Arrestins

Known as: Arrestins [Chemical/Ingredient] 
Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors.
National Institutes of Health

Papers overview

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Review
2007
Review
2007
To ensure that extracellular stimuli are translated into intracellular signals of appropriate magnitude and specificity, most… (More)
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Review
2006
Review
2006
The 4 mammalian arrestins serve as almost universal regulators of the largest known family of signaling proteins, G-protein… (More)
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Review
2006
Review
2006
In vertebrates, the arrestins are a family of four proteins that regulate the signaling and trafficking of hundreds of different… (More)
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Review
2006
Review
2006
Stimulation of cell-surface seven-transmembrane receptors (7TMRs) elicits biological responses to a wide range of extracellular… (More)
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Highly Cited
2006
Highly Cited
2006
Physiological effects of beta adrenergic receptor (beta2AR) stimulation have been classically shown to result from G(s)-dependent… (More)
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Review
2005
Review
2005
The transmission of extracellular signals to the interior of the cell is a function of plasma membrane receptors, of which the… (More)
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Review
2003
Review
2003
Beta-arrestins are cytosolic proteins that bind to activated and phosphorylated G-protein-coupled receptors [7MSRs (seven… (More)
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Review
2002
Review
2002
beta-Arrestins are versatile adapter proteins that form complexes with most G-protein-coupled receptors (GPCRs) following agonist… (More)
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Highly Cited
2000
Highly Cited
2000
Visual arrestin, betaarrestin1, and betaarrestin2 comprise a family of intracellular proteins that desensitize G protein-coupled… (More)
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Highly Cited
1996
Highly Cited
1996
beta-Arrestins are proteins that bind phosphorylated heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) and… (More)
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