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Arabinofuranosylcytosine Triphosphate

Known as: Ara-CTP, Cytarabine Triphosphate, Cytosine Arabinoside Triphosphate 
A triphosphate nucleotide analog that is the metabolized, biologically active form of cytarabine. This metabolite is a competitive inhibitor of DNA… 
National Institutes of Health

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8 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Nucleic Acid Synthesis Inhibitors

Papers overview

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Highly Cited
1985
Highly Cited
1985
Identification of an active site peptide of skeletal myosin after photoaffinity labeling with N-(4-azido-2-nitrophenyl)-2-aminoethyl diphosphate.
The active site of skeletal myosin has been photoaffinity labeled (approximately equal to 50%) by the ADP analog N-(4-azido-2… 
1985
1985
Dependence of u.v.-induced DNA excision repair on deoxyribonucleoside triphosphate concentrations in permeable human fibroblasts: a model for the inhibition of repair by hydroxyurea.
We have tested the hypothesis that the inhibition by hydroxyurea of repair patch ligation and chromatin rearrangement during u.v… 
Highly Cited
1981
Highly Cited
1981
Some observations relating to the oximate ion promoted unblocking of oligonucleotide aryl esters.
The action of the N1, N1, N3, N3-tetramethylguanidinium salts of a number of oximes on 5'-O-methoxytetrahydropyranylthymidylyl-(3… 
1981
1981
Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations
The Thy- mutants of Chinese hamster ovary cells have a 5- to 10-fold elevated pool of deoxycytidine 5'-triphosphate (dCTP) and… 
Highly Cited
1977
Highly Cited
1977
Interactions of a photoaffinity analog of GTP with the proteins of microtubules.
Tubulin dimers isolated from brain contain two GTP binding sites, a nonexchangeable site and an exchangeable site. To localize… 
Highly Cited
1975
Highly Cited
1975
Metabolism and selective effects of 1-beta-D-arabinofuranosylcytosine in L1210 and Host tissues in vivo.
The selectivity of action of 1-beta-D-arabinofuranosylcytosine (ara-C) against leukemic cells was studied in vivo. Dynamic state… 
Highly Cited
1975
Highly Cited
1975
Diguanosinetetraphosphatase from rat liver: Acitivity on diadenosine tetraphosphate and inhibition by adenosine tetraphosphate.
The hydrolysis of diadenosine tetraphosphate, a compound previously described by others to occur in liver at concentrations of… 
1974
1974
Substrate and effector binding to ribonucleoside triphosphate reductase of Lactobacillus leichmannii.
Highly Cited
1970
Highly Cited
1970
Properties of RNA transcriptase in reovirus subviral particles.
Subviral particles containing reovirus RNA transcriptase have been isolated from extracts of virus-infected mouse fibroblast… 
Highly Cited
1969
Highly Cited
1969
Inhibition of 5'-nucleotidase from Ehrlich ascites-tumour cells by nucleoside triphosphates.
1. 5'-Nucleotidase activity was obtained in a soluble form after treatment of a particulate fraction from Ehrlich ascites-tumour…