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Apatorsen
A second-generation antisense oligonucleotide targeting heat shock protein 27 (Hsp27) with potential antitumor and chemosensitizing activities…
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National Institutes of Health
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OGX-427
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2018
2018
Heat shock protein 27 knockdown using nucleotide ‐ based therapies enhances sensitivity to 5 ‐ FU chemotherapy in SW 480 human colon cancer cells
Takehiro Shimada
,
M. Tsuruta
,
+8 authors
Y. Kitagawa
2018
Corpus ID: 131763115
Heat shock protein 27 (Hsp27) is a chaperone protein of low molecular weight that is produced in response to various stresses and…
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2017
2017
Evaluation of Gemcitabine/Carboplatin Alone or in Combination With Apatorsen
R. Simoneaux
2017
Corpus ID: 80167035
2015
2015
Heat Shock Protein Inhibitor May Benefit Bladder Cancer Patients
M. Fuerst
2015
Corpus ID: 181489813
Advanced bladder cancer patients with poor prognosis appear to benefit from adding apatorsen 600 mg to first-line chemotherapy…
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2015
2015
Addition of Hsp27 inhibitor apatorsen to first-line gemcitabine/carboplatin in advanced squamous cell lung cancer: design of the Cedar (TM) trial
P. Schmid
,
D. Muthukumar
,
+14 authors
L. Lim
2015
Corpus ID: 80051074
2014
2014
Apatorsen sodium. HSPB1 (HSP27) expression inhibitor, treatment of prostate cancer, treatment of pancreatic adenocarcinoma, treatment of bladder cancer, treatment of non-small cell lung cancer
K. Haddley
Drugs of the future
2014
Corpus ID: 75526454