Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Antisickling Agents

Known as: Agents, Antisickling, antisickling agent 
Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Summary. Among the various potential antisickling agents tested, hydroxyurea (HU) has been the most effective compound used for… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Painful crises in patients with sickle cell anemia are caused by vaso-occlusion and infarction. Occlusion of blood vessels… Expand
Is this relevant?
1995
1995
Clotrimazole (CLT) has recently been shown to be a potent and specific inhibitor of the Ca(2+)-activated K+ channel and to… Expand
  • table 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Amino acid analysis showed that solvent extracts of Cajanus cajan L. Millsp. (Fabaceae) seeds (white species) contain, as free… Expand
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Several aromatic compounds have been found to inhibit the gelling of sickle cell hemoglobin. We have tried to correlate the… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1981
1981
Biomedical scientists withachemical orientation recognize thattherational design oftherapeutic compounds must… Expand
Is this relevant?
Highly Cited
1981
Highly Cited
1981
Cetiedil has been reported to relieve painful crises in sickle cell anemia and to have antisickling properties in vitro. The drug… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1978
Highly Cited
1978
Abstract The occurrence and progression of strokes in patients with sickle cell disease and the resultant structural and… Expand
  • table I
  • table II
  • table II
  • table III
Is this relevant?
Highly Cited
1978
Highly Cited
1978
Hypocupremia occurred in an adult with sickle cell anemia who received zinc as an antisickling agent for two years. The… Expand
Is this relevant?
1975
1975
A new approach to the prevention of sickling in vitro by use of the bifunctional crosslinking reagent, dimethyl adipimidate, is… Expand
Is this relevant?