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Antibody-Drug Conjugate SC16LD6.5

Known as: Anti-SC16 ADC SC16LD6.5, SC16LD6.5 
An antibody-drug conjugate (ADC) containing an antibody directed against the scr-like kinase Fyn3 (SC-16), conjugated to the cytotoxic agent D6.5… 
National Institutes of Health

Papers overview

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2017
2017
Abstract 3093: Expression of DLL3 in metastatic melanoma, glioblastoma and high-grade extrapulmonary neuroendocrine carcinomas as potential indications for rovalpituzumab tesirine (Rova-T; SC16LD6.5…
Expression of DLL3 was examined in additional tumor types, as it was found to be highly expressed in tumor-initiating cells (TIC… 
2016
2016
LANL SC16 Green500
2016
2016
Abstract 4778: Covalent bonding of a C8-conjugated pyrrolobenzodiazepine (PBD) monomer and dimer to a terminal guanine residue of DNA duplex and hairpin fragments
The pyrrolobenzodiazepines (PBDs) are a family of covalent-binding DNA-interactive minor-groove binding agents that are of… 
2003
2003
Simulation of solidification and heat treatment of nickel-base superalloy SC16
Thermodynamic equilibrium and Gulliver – Scheil as well as diffusion calculations using the DICTRA program have been made to… 
Highly Cited
1995
Highly Cited
1995
First-principles pseudopotential study of the phase stability of the III-V semiconductors GaAs and AlAs.
A first-principles pseudopotential study of the phase stability of the III-V semiconductors GaAs and AlAs is reported. For both… 
Review
1990
Review
1990
International collaboration in the public sector (OSI standards)
Public sector commitment to standards-based solutions to information technology requirements has played a major role in the… 
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