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Antibodies, Catalytic

Known as: Catalytic Antibody, Antibody, Catalytic, Antibodies, Catalytic [Chemical/Ingredient] 
Antibodies that can catalyze a wide variety of chemical reactions. They are characterized by high substrate specificity and share many mechanistic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Current strategies for creating enzyme-like catalysts range from rational[1] and computational design[2] to evolutionary searches… Expand
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Highly Cited
2006
Highly Cited
2006
Autoantibody-mediated tissue destruction is among the main features of organ-specific autoimmunity. This report describes "an… Expand
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Highly Cited
2004
Highly Cited
2004
Self-immolative dendrimers have recently been developed and introduced as a potential platform for a multi-prodrug. These unique… Expand
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Highly Cited
2000
Highly Cited
2000
Abstract A single-step enantioselective synthesis of the Wieland–Miescher ketone ( 5 ) is presented. We show that l -proline as… Expand
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Highly Cited
1998
Highly Cited
1998
This paper describes the substrate specificity, synthetic scope, and efficiency of aldolase catalytic antibodies 38C2 and 33F12… Expand
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Highly Cited
1997
Highly Cited
1997
Structural and mechanistic studies show that when the selection criteria of the immune system are changed, catalytic antibodies… Expand
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Highly Cited
1995
Highly Cited
1995
Antibodies that catalyze the aldol reaction, a basic carbon-carbon bond-forming reaction, have been generated. The mechanism for… Expand
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Highly Cited
1994
Highly Cited
1994
The three-dimensional structure of an unusually active hydrolytic antibody with a phosphonate transition state analog (hapten… Expand
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Highly Cited
1991
Highly Cited
1991
Immunochemistry has historically focused on the nature of antigenicity and antibody-antigen recognition. However, in the last 5… Expand
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Highly Cited
1989
Highly Cited
1989
THE high binding affinity and specificity of antibodies for a wide range of ligands has recently been exploited in the generation… Expand
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