Antiapoptotic Agent

Known as: antiapoptotic 
Something that prevents apoptosis. Apoptosis is a type of cell death in which a series of molecular steps in a cell leads to its death.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
We followed our initial genome-wide association study (GWAS) of 527,869 SNPs on 1,172 individuals with prostate cancer and 1,157… (More)
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Highly Cited
2006
Highly Cited
2006
We show that the antiapoptotic proteins BCL-2, BCL-XL, MCL-1, BFL-1, and BCL-w each bear a unique pattern of interaction with a… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are small noncoding RNA molecules that regulate protein expression by targeting the mRNA of protein-coding… (More)
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Highly Cited
2005
Highly Cited
2005
Apoptosis and autophagy are both tightly regulated biological processes that play a central role in tissue homeostasis… (More)
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Highly Cited
2005
Highly Cited
2005
Chronic lymphocytic leukemia (CLL) is the most common human leukemia and is characterized by predominantly nondividing malignant… (More)
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Highly Cited
2003
Highly Cited
2003
Regulated apoptosis is essential for both the development and the subsequent maintenance of the immune system. Interleukins… (More)
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Highly Cited
2001
Highly Cited
2001
With the recognition of the central role of mitochondria in apoptosis, there is a need to develop specific tools to manipulate… (More)
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Highly Cited
2000
Highly Cited
2000
To assess the role of BAX in drug-induced apoptosis in human colorectal cancer cells, we generated cells that lack functional BAX… (More)
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Highly Cited
1998
Highly Cited
1998
We examined the role of vascular endothelial growth factor (VEGF) in preventing apoptosis in primary human umbilical vein… (More)
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Highly Cited
1997
Highly Cited
1997
We have found that insulin-like growth factor I (IGF-I) can protect fibroblasts from apoptosis induced by UV-B light… (More)
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