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The introduction of β-cell autoantigens via the gut through Lactococcus lactis (L. lactis) has been demonstrated to be a… Expand We recently developed new electrochemiluminescence (ECL) insulin autoantibody (IAA) and glutamic acid decarboxylase 65… Expand
Diabet. Med. 29, 1335–1338 (2012)
C/EBP homologous protein (CHOP) has been proposed as a key transcription factor for endoplasmic reticulum (ER) stress-mediated… Expand Insulin has been reported as a major autoantigen in both human and murine type 1 diabetes (T1D). Insulin1‐knockout NOD mice with… Expand Autoimmune hypoglycemia is characterized by insulin autoantibody, hyperinsulinemia and fasting hypoglycemia without previous… Expand The loss of beta cells in type 1 diabetes is the consequence of a T cell-dependent autoimmune attack. Autoantibodies against… Expand SummaryInsulin autoantibodies, like islet cell antibodies, are found not only in the sera of newly diagnosed Type 1 (insulin… Expand NOD mice spontaneously develop anti-insulin autoantibodies associated with the subsequent development of diabetes. NOD mice that… Expand IgG antibodies to insulin are present in insulin-treated patients and are detected in the prodrome of untreated type I diabetes… Expand