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Anti-angiopoietin Monoclonal Antibody AMG 780

Known as: AMG 780 
An immunoglobulin (Ig) G2 monoclonal antibody targeting the proangiogenic cytokines angiopoietin 1 (Ang1) and 2 (Ang2), with potential anti… Expand
National Institutes of Health

Papers overview

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2016
2016
Purpose: To assess the toxicity, pharmacokinetics, tumor vascular response, tumor response, and pharmacodynamics of AMG 780, a… Expand
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2014
2014
Targeting the angiopoietins with trebananib (a peptibody that inhibits the interaction between the endothelial cell-selective… Expand
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2014
2014
2542 Background: AMG 780 is a fully human monoclonal antibody binding Ang1/2, thereby inhibiting their interaction with Tie2… Expand
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