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Anti-NaPi2b/MMAE Antibody-Drug Conjugate DNIB0600A
Known as:
ADC DNIB0600A
, DNIB0600A
An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against the sodium-dependent phosphate transport protein 2B (NaPi2b), and…
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National Institutes of Health
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NCIt Antineoplastic Agent Terminology
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2016
2016
A randomized, open-label, phase II study of anti-NaPi2b antibody-drug conjugate (ADC) lifastuzumab (Lifa) vedotin (DNIB0600A) compared to pegylated liposomal doxorubicin (PLD) in patients (pts) with…
Susana Banerjee
,
A. Oza
,
+17 authors
Joyce F. Liu
2016
Corpus ID: 79061445
5569Background: NaPi2b is a transmembrane, sodium-dependent phosphate transporter expressed in ~90% of OC. Lifa, a humanized anti…
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2015
2015
Abstract POSTER-THER-1441: Biomarker evaluation of phase 1 clinical trials of antibody-drug conjugates (ADCs) in platinum resistant ovarian cancer
Yulei N. Wang
,
R. Firestein
,
+18 authors
Daniel Mayslar
2015
Corpus ID: 58593453
Purpose: DNIB0600A and DMUC5754A are two ADCs that conjugate the anti-mitotic agent MMAE with anti-NaPi2b and anti-MUC16…
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2009
2009
Épitope napi2b (slc34a2) de transport à travers les membranes pour une thérapie par anticorps, anticorps dirigés contre celui-ci, et cible pour une thérapie du cancer
G. Ritter
,
Beatrice W. T. Yin
,
+7 authors
Ramziya Kiyamova
2009
Corpus ID: 192406875
La presente invention porte d'une maniere generale sur le transporteur membranaire NaPi2b (SLC34A2) comme cible pour une therapie…
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