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Anti-MMP-9 Monoclonal Antibody GS-5745

Known as: GS-5745 
A humanized monoclonal antibody against matrix metalloproteinase 9 (MMP-9), with potential antineoplastic activity. Upon administration, anti-MMP-9… Expand
National Institutes of Health

Papers overview

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2018
2018
Abstract Background and Aims Matrix metalloproteinase-9 [MMP9] is implicated in the pathogenesis of ulcerative colitis [UC] via… Expand
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2018
2018
PURPOSE Andecaliximab (GS-5745) is a highly selective monoclonal antibody against matrix metalloproteinase-9 (MMP9), a… Expand
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2018
2018
Purpose: Matrix metalloproteinase-9 (MMP9) is implicated in protumorigenic processes. Andecaliximab (GS-5745, a monoclonal… Expand
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2018
2018
Abstract Background and Aims Matrix metalloproteinase-9 [MMP9] is implicated in the pathogenesis of Crohn’s disease and may serve… Expand
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2017
2017
Matrix metalloproteinase 9 (MMP9) is a member of a large family of proteases that are secreted as inactive zymogens. It is a key… Expand
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2017
2017
4Background: Andecaliximab (ADX) is a monoclonal antibody that inhibits matrix metalloproteinase 9, an extracellular enzyme… Expand
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2016
2016
Matrix metalloproteinase‐9 is a proteolytic enzyme whose expression is increased in ulcerative colitis. 
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2016
2016
4033Background: GS-5745 is a monoclonal antibody that inhibits matrix metalloproteinase 9 (MMP9), an extracellular enzyme… Expand
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Highly Cited
2015
Highly Cited
2015
Expression of matrix metalloproteinase 9 (MMP9) is elevated in a variety of inflammatory and oncology indications, including… Expand
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2015
2015
4030 Background: GS-5745 is a monoclonal antibody that inhibits matrix metalloproteinase 9 (MMP9), an extracellular enzyme… Expand
Is this relevant?