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Anti-FGFR2 Antibody-drug Conjugate BAY1187982
Known as:
ADC BAY1187982
, BAY 1187982
, BAY1187982
An antibody-drug conjugate (ADC) directed against the fibroblast growth factor receptor type 2 (FGFR2) and conjugated to an as of yet unidentified…
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National Institutes of Health
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Related topics
Related topics
1 relation
Receptor Tyrosine Kinase Inhibition
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Downregulating oncogenic receptor: From bench to clinic
G. Zhu
,
Ali-Akmbar Saboor-Yaraghi
,
Y. Yarden
,
Joana C Santos
,
Neil Jc
2016
Corpus ID: 53061630
In 1989-1991, George Zhu first postulate oncogenic receptor (Voice of America,1992,12:31;Curr Pharm Biotechnol,2013,14:859-863…
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2015
2015
Abstract 1684: Preclinical anti-tumor efficacy of FGFR2-ADC BAY 1187982 in patient-derived gastric, breast and ovarian cancer models
A. Sommer
,
C. Kopitz
,
+9 authors
K. Ziegelbauer
2015
Corpus ID: 70410598
Antibody-drug conjugates (ADC) represent a promising therapeutic approach for treatment of cancer. We have developed a novel ADC…
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2015
2015
Abstract 1683: Pharmacokinetic/pharmacodynamic (PK/PD) and toxicokinetic/toxicodynamic (TK/TD) modeling of preclinical data of FGFR2-ADC (BAY 1187982) to guide dosing in phase 1
S. Wittemer-Rump
,
A. Sommer
,
+8 authors
K. Prins
2015
Corpus ID: 79068117
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA BAY 1187982 is an antibody drug conjugate (ADC…
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