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Anti-ETBR/MMAE Antibody-Drug Conjugate DEDN6526A

Known as: ADC DEDN6526A, DEDN6526A 
An antibody-drug conjugate (ADC) composed of a humanized immunoglobulin (Ig) G1 monoclonal antibody against anti-endothelin B receptor (ETBR) and… 
National Institutes of Health

Papers overview

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2014
2014
Abstract CT233: A first-in-human phase I study of the safety and pharmacokinetic (PK) activity of DEDN6526A, an anti-endothelin B receptor (ETBR) antibody-drug conjugate (ADC), in patients with…
Background: ETBR, a G-protein coupled receptor that can activate RAF/MEK signaling, is overexpressed in metastatic melanoma… 
2013
2013
Sensitivity of Prestaining RNA with Ethidium Bromide Before Electrophoresis and Performance of Subsequent Northern Blots Using Heterologous DNA Probes
Adding ethidium bromide (EtBr) at low concentrations to RNA samples before running formaldehyde–agarose gels affords the… 
2013
2013
Pathogenic mutations and novel variants in MLH1 and MSH2 in a South African colon cancer cohort
2000
2000
Ethidium bromide binding to native and denatured poly(dA)poly(dT)
Isotherms of the EtBr adsorption on native and denatured poly(dA)poly(dT) in the temperature interval 20–70°C were obtained. The… 
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