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Anti-EGFR TAP Antibody-drug Conjugate IMGN289
Known as:
Anti-EGFR-SMCC-DM1
, IMGN289
A targeted antibody payload (TAP)-based immunoconjugate consisting of a human monoclonal antibody directed against the epidermal growth factor…
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National Institutes of Health
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2013
2013
Abstract 5467: IMGN289, an EGFR-targeting antibody-maytansinoid conjugate with potent activity against non-small cell lung cancer (NSCLC) regardless of dependency on EGFR pathway.
T. Chittenden
,
Y. Setiady
,
+8 authors
J. Lambert
2013
Corpus ID: 71591678
NSCLC accounts for approximately 85% of all lung cancers. Based on tumor histology, NSCLC can be subdivided into adenocarcinoma…
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2013
2013
Abstract 5483: Preclinical evaluation of IMGN289, an anti-EGFR antibody-maytansinoid conjugate for the treatment of squamous cell carcinoma of the head and neck.
Jose F. Ponte
,
Y. Setiady
,
+5 authors
J. Pinkas
2013
Corpus ID: 71680374
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Squamous cell carcinoma of the head and neck (SCCHN…
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