Anti-Drug Antibody

Known as: ADA, Anti-Drug Antibodies 
An antibody that binds to an administered drug. Expression of these antibodies is thought to be induced by (repeated) drug administration.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND & AIMS There is controversy about whether levels of anti-tumor necrosis factor (TNF) and antidrug antibodies (ADAs… (More)
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2015
2015
Drug interference complicates assessment of immunogenicity of biologicals and results in an underestimation of anti-drug antibody… (More)
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2014
2014
OBJECTIVES To investigate the relationship between antidrug antibodies (ADA), adalimumab concentrations and clinical response in… (More)
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2013
2013
The objectives of this study are to evaluate the effect of anti-drug antibodies on the clinical efficacy and withdrawal rate of… (More)
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2013
2013
The rapidly increasing number of therapeutic antibodies in clinical development and on the market requires corresponding… (More)
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Highly Cited
2013
Highly Cited
2013
The study objective was to evaluate the pharmacokinetics (PK), antidrug antibody (ADA), and safety of motavizumab-YTE… (More)
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Highly Cited
2012
Highly Cited
2012
Antibody-based drugs such as infliximab (IFX) are effective for the treatment of inflammatory bowel disease (IBD) and other… (More)
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2012
2012
BACKGROUND Anti-drug antibodies can be elicited by infliximab and adalimumab, but the rate of their decay after therapy is… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE The aim of this study was to test the hypothesis that the reason for non-response (caused by immunogenicity or not) to… (More)
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2011
2011
The presence of anti-drug antibodies (ADA) in adalimumab-treated patients is associated with reduced serum adalimumab levels and… (More)
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