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Anti-DKK1 Monoclonal Antibody BHQ880
A humanized monoclonal antibody directed against Wnt antagonist Dickkopf-1 (DKK1) with potential anti-osteolytic activity. Anti-DKK1 monoclonal…
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National Institutes of Health
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BHQ880
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Increased anabolic bone response in Dkk1 KO mice following tibial compressive loading.
A. Morse
,
Frank C. Ko
,
+4 authors
D. Little
Bone
2019
Corpus ID: 202580128
A viable Dkk1 knockout (KO) mouse strain in which embryonic lethality is rescued by developmental Wnt3 heterozygosity (Dkk1…
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2018
2018
MiR-613 inhibits proliferation and invasion and induces apoptosis of rheumatoid arthritis synovial fibroblasts by direct down-regulation of DKK1
L. Liu
,
Yanhua Zuo
,
Y. Xu
,
Zongfang Zhang
,
Y. Li
,
J. Pang
Cellular & Molecular Biology Letters
2018
Corpus ID: 121298186
BackgroundThis study aimed to investigate the effects of miR-613 on the proliferation, invasion and apoptosis of rheumatoid…
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2018
2018
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
A. Morse
,
T. Cheng
,
+5 authors
D. Little
Calcified Tissue International
2018
Corpus ID: 44170123
Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in…
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2017
2017
Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation
M. McDonald
,
A. Morse
,
+9 authors
D. Little
Calcified Tissue International
2017
Corpus ID: 11599277
Wnt antagonist Dkk1 is a negative regulator of bone formation and Dkk1+/− heterozygous mice display a high bone mass phenotype…
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2014
2014
Dkk1 intheperi-cloacamesenchymeregulatesformationofanorectal and genitourinarytracts
M. T. Bryan
,
Guo Chaoshe
,
Sun Ye
,
Borer G. Joseph
,
Guo Chun-ming
,
L. Xue
2014
Corpus ID: 109163630
2010
2010
Increased Dickkopf-1 expression accelerates bone cell apoptosis in femoral head osteonecrosis.
J. Ko
,
F. Wang
,
Ching-Jen Wang
,
T. Wong
,
Wen-Yi Chou
,
Shin-Ling Tseng
Bone
2010
Corpus ID: 41657958
Intensive bone cell apoptosis contributes to osteonecrosis of femoral head (ONFH). Dickkopf-1 (DKK1) reportedly mediates various…
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2009
2009
Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours
T. Johansson
,
G. Westin
,
B. Skogseid
BMC Cancer
2009
Corpus ID: 16102430
BackgroundASCL1 role in pancreatic endocrine tumourigenesis has not been established. Recently it was suggested that ASCL1…
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