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Anti-CEACAM6 AFAIKL2 Antibody Fragment/Jack Bean Urease Immunoconjugate L-DOS47
Known as:
L-DOS47
A lyophilized formulation of DOS47, an immunoconjugate composed of AFAIKL2, a recombinant camelid single-domain antibody which recognizes…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Development and Characterization of a Camelid Single Domain Antibody–Urease Conjugate That Targets Vascular Endothelial Growth Factor Receptor 2
B. Tian
,
W. Wong
,
Marni D. Uger
,
P. Wisniewski
,
H. Chao
Front. Immunol.
2017
Corpus ID: 9694227
Angiogenesis is the process of new blood vessel formation and is essential for a tumor to grow beyond a certain size. Tumors…
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2015
2015
Production and characterization of a camelid single domain antibody-urease enzyme conjugate for the treatment of cancer.
B. Tian
,
W. Wong
,
E. Hegmann
,
K. Gaspar
,
Praveen Kumar
,
H. Chao
Bioconjugate chemistry
2015
Corpus ID: 21718362
A novel immunoconjugate (L-DOS47) was developed and characterized as a therapeutic agent for tumors expressing CEACAM6. The…
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2013
2013
Abstract 2851: Development of an alkalizing antibody-enzyme conjugate for NSCLC treatment that is in Phase I clinical testing.
H. Chao
,
B. Tian
,
K. Gaspar
,
J. Docherty
,
W. Wong
2013
Corpus ID: 70474707
Many solid human tumors generate an acidic and hypoxic microenvironment as a result of altered metabolic pathways and aberrant…
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