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Anti-CD73 Monoclonal Antibody MEDI9447

Known as: MEDI9447 
A monoclonal antibody against the ectoenzyme CD73 (cluster of differentiation 73), also known as 5'-nucleotidase (5'-NT; ecto-5'-nucleotidase) with… Expand
National Institutes of Health

Papers overview

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2018
2018
4123Background: Oleclumab is a human mAb that binds to CD73 and inhibits production of immunosuppressive adenosine. This is a… Expand
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Highly Cited
2016
Highly Cited
2016
ABSTRACT MEDI9447 is a human monoclonal antibody that is specific for the ectoenzyme CD73 and currently undergoing Phase I… Expand
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2016
2016
ABSTRACT CD73 (ecto-5′-nucleotidase) has recently been established as a promising immuno-oncology target. Given its role in… Expand
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2016
2016
TPS3096Background: The success of immune checkpoint inhibitors in various cancers has triggered the identification of novel… Expand
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2015
2015
MEDI9447 is a monoclonal antibody specific for the ectoenzyme, CD73. Data is presented in support of the hypothesis that… Expand
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2015
2015
CD73 is an ectonucleotidase that converts extracellular AMP to Adenosine. Within the tumor microenvironment, adenosine produced… Expand
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