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Anti-CD20-engineered Toxin Body MT-3724

Known as: MT-3724 
An engineered toxin body (ETB) composed of the single-chain variable fragment (ScFv) from an antibody targeting CD20 that is linked to a modified… Expand
National Institutes of Health

Papers overview

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2019
2019
MT-3724 is a novel recombinant fusion protein consisting of a CD20 binding variable fragment (scFv) fused to Shiga-like toxin-I… Expand
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2018
2018
Mantle cell lymphoma (MCL) is a non-Hodgkin lymphoma (NHL) subtype with aggressive clinical demonstration characterized by the… Expand
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2018
2018
7580Background: MT-3724 is a novel recombinant fusion protein consisting of a CD20 binding variable fragment (scFv) fused to… Expand
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2017
2017
Mantle cell lymphoma (MCL) accounts for 6-8% of all non-Hodgkin lymphoma cases and is a therapeutic challenge. MCL is… Expand
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2017
2017
Background Novel mechanisms of action (MOA) are needed to treat R/R NHL. CD20 is ubiquitously and persistently expressed in B… Expand
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2014
2014
The B-cell membrane protein CD20 is expressed by both benign and neoplastic lymphocytes. It has been a superb target for… Expand
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