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Anti-CD20-engineered Toxin Body MT-3724

Known as: MT-3724 
An engineered toxin body (ETB) composed of the single-chain variable fragment (ScFv) from an antibody targeting CD20 that is linked to a modified… Expand
National Institutes of Health

Papers overview

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2020
2020
TPS8074Background: Engineered toxin bodies (ETBs) are comprised of a proprietarily engineered form of Shiga-like Toxin A subunit… Expand
2019
2019
MT-3724 is a novel recombinant fusion protein consisting of a CD20 binding variable fragment (scFv) fused to Shiga-like toxin-I… Expand
2018
2018
7580Background: MT-3724 is a novel recombinant fusion protein consisting of a CD20 binding variable fragment (scFv) fused to… Expand
2018
2018
Mantle cell lymphoma (MCL) is a non-Hodgkin lymphoma (NHL) subtype with aggressive clinical demonstration characterized by the… Expand
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2017
2017
Molecular Templates is developing engineered toxin bodies (ETBs), potent recombinant immunotoxins that combine the specificity of… Expand
2016
2016
Molecular Templates has developed engineered toxin bodies (ETBs), potent recombinant immunotoxins that combine the specificity of… Expand
2016
2016
Background Anti-CD20 monoclonal antibody (MAb) therapy is widely employed in the treatment of non-Hodgkin9s B-cell lymphoma (NHL… Expand
2014
2014
The B-cell membrane protein CD20 is expressed by both benign and neoplastic lymphocytes. It has been a superb target for… Expand