Angiopoietin-2

Known as: Angiopoietin-2 [Chemical/Ingredient], Ang2, ANGPT2 
Encoded by Human ANGPT2 Gene, Angiopoietin 2 is a 496-amino acid 57 kD (precursor) homodimeric secreted protein that contains a fibrinogen-like C… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
05010015019972017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The angiopoietins Ang-1 and Ang-2 have been identified as ligands of the receptor tyrosine kinase Tie-2 (refs. 1,2). Paracrine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
BACKGROUND Acute respiratory distress syndrome (ARDS) is a devastating complication of numerous underlying conditions, most… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The angiopoietins Ang-1 and Ang-2 have been identified as ligands with opposing functions of the receptor tyrosine kinase Tie-2… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
VEGF and Angiopoietin-1 requisitely collaborate during blood vessel development. While Angiopoietin-1 obligately activates its… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Modulation of Tie2 receptor activity by its angiopoietin ligands is crucial for angiogenesis, blood vessel maturation, and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
In contrast with the prevailing view that most tumors and metastases begin as avascular masses, evidence is presented here that a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 (Ang1) has been recently identified as the major physiological ligand for the tyrosine kinase receptor Tie2 and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Glioblastomas are highly vascular tumors which overexpress the angiogenesis factor vascular endothelial growth factor (VEGF… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 and its putative natural antagonist, angiopoietin-2, were recently isolated, and the critical role of angiopoietin… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Angiogenesis is thought to depend on a precise balance of positive and negative regulation. Angiopoietin-1 (Ang1) is an… (More)
Is this relevant?