Androgen Response Element
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In the United States, prostate cancer (PCa) is the most commonly diagnosed non-cutaneous cancer in males and the second leading… Expand Recent insights into the regulation of the androgen receptor (AR) activity led to novel therapeutic targeting of AR function in… Expand Targeting androgen receptor may prevent hepatitis B virus–induced liver cancer. Destroying the Source of Liver Cancer… Expand Androgen receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone… Expand Transcription of the prostate-specific antigen (PSA) gene escapes regulation by androgens in advanced prostate cancer. To… Expand The X-linked androgen receptor (AR) gene contains two polymorphic trinucleotide repeat segments that code for polyglutamine and… Expand Prostate-specific antigen (PSA) is expressed at a high level in the luminal epithelial cells of the prostate and is absent or… Expand Transcription of the prostate-specific antigen (PSA) gene is androgen regulated. The PSA promoter contains at position −170 the… Expand Androgens mediate a number of diverse responses through the androgen receptor, a 110 kD ligand-activated nuclear receptor… Expand The mechanism of antiandrogenic activity of vinclozolin (3-(3,5-dichlorophenyl)-5-methyl-5-vinyloxazolidine-2,4-dione), a… Expand