Anaplastic Carcinoma Cell
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Orthotopic mouse models of human cancer represent an important in vivo tool for drug testing and validation. Most of… Expand Anaplastic thyroid carcinoma (ATC) is the most aggressive thyroid cancer variant, accounting for 1–2% of all cases, but 33% of… Expand Therapy for patients with advanced thyroid carcinoma is limited. Clinical and in vitro studies suggest that some patients with… Expand Anaplastic thyroid carcinoma is an aggressive neoplasm and resistant to all sorts of treatment due to its rapid growth and… Expand Activating point mutations of the BRAF gene have been recently reported in papillary thyroid carcinomas. In this study, we… Expand The RAS-RAF-MEK-ERK-MAP kinase pathway mediates the cellular response to extracellular signals that regulate cell proliferation… Expand Being one of the most lethal human neoplasms and refractory to such conventional treatment as chemo- and radiotherapy, anaplastic… Expand High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that… Expand Anaplastic carcinoma of thyroid is uncommon and is associated with a poor prognosis. an effective treatment of this carcinoma has… Expand The development and progression of thyroid tumors is signaled by phenotype-specific mutations of genes involved in growth control… Expand