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Anaplastic Carcinoma Cell

Known as: Anaplastic Malignant Epithelial Cell, Pleomorphic Carcinoma Cell, Pleomorphic Malignant Epithelial Cell 
A malignant epithelial cell, usually of large size, characterized by the lack of differentiation. Anaplastic carcinoma cells have large… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Orthotopic mouse models of human cancer represent an important in vivo tool for drug testing and validation. Most of… Expand
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2008
2008
Anaplastic thyroid carcinoma (ATC) is the most aggressive thyroid cancer variant, accounting for 1–2% of all cases, but 33% of… Expand
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Highly Cited
2004
Highly Cited
2004
Therapy for patients with advanced thyroid carcinoma is limited. Clinical and in vitro studies suggest that some patients with… Expand
2004
2004
Anaplastic thyroid carcinoma is an aggressive neoplasm and resistant to all sorts of treatment due to its rapid growth and… Expand
Highly Cited
2003
Highly Cited
2003
Activating point mutations of the BRAF gene have been recently reported in papillary thyroid carcinomas. In this study, we… Expand
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Highly Cited
2003
Highly Cited
2003
The RAS-RAF-MEK-ERK-MAP kinase pathway mediates the cellular response to extracellular signals that regulate cell proliferation… Expand
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Highly Cited
2002
Highly Cited
2002
Being one of the most lethal human neoplasms and refractory to such conventional treatment as chemo- and radiotherapy, anaplastic… Expand
Highly Cited
2000
Highly Cited
2000
High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that… Expand
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1999
1999
Anaplastic carcinoma of thyroid is uncommon and is associated with a poor prognosis. an effective treatment of this carcinoma has… Expand
Highly Cited
1993
Highly Cited
1993
The development and progression of thyroid tumors is signaled by phenotype-specific mutations of genes involved in growth control… Expand
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