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Anaplastic Carcinoma Cell

Known as: Anaplastic Malignant Epithelial Cell, Pleomorphic Carcinoma Cell, Pleomorphic Malignant Epithelial Cell 
A malignant epithelial cell, usually of large size, characterized by the lack of differentiation. Anaplastic carcinoma cells have large… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Orthotopic mouse models of human cancer represent an important in vivo tool for drug testing and validation. Most of… Expand
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2005
2005
  • Y. Nikiforov
  • The Journal of clinical endocrinology and…
  • 2005
  • Corpus ID: 42199539
Anaplastic (undifferentiated) thyroid carcinoma is one of the most aggressive malignancies known to humans. It carries an almost… Expand
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2004
2004
Anaplastic thyroid carcinoma is an aggressive neoplasm and resistant to all sorts of treatment due to its rapid growth and… Expand
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Highly Cited
2004
Highly Cited
2004
Therapy for patients with advanced thyroid carcinoma is limited. Clinical and in vitro studies suggest that some patients with… Expand
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Highly Cited
2003
Highly Cited
2003
Activating point mutations of the BRAF gene have been recently reported in papillary thyroid carcinomas. In this study, we… Expand
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Highly Cited
2003
Highly Cited
2003
The RAS-RAF-MEK-ERK-MAP kinase pathway mediates the cellular response to extracellular signals that regulate cell proliferation… Expand
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Highly Cited
2002
Highly Cited
2002
Being one of the most lethal human neoplasms and refractory to such conventional treatment as chemo- and radiotherapy, anaplastic… Expand
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Highly Cited
2000
Highly Cited
2000
High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that… Expand
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1999
1999
Anaplastic carcinoma of thyroid is uncommon and is associated with a poor prognosis. an effective treatment of this carcinoma has… Expand
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Highly Cited
1993
Highly Cited
1993
The development and progression of thyroid tumors is signaled by phenotype-specific mutations of genes involved in growth control… Expand
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