Amyloid Fibrils

Known as: Fibrils, Amyloid 
 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Amyloid fibrils characterize a diverse group of human diseases that includes Alzheimer's disease, Creutzfeldt-Jakob and type II… (More)
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Highly Cited
2008
Highly Cited
2008
We describe a full structural model for amyloid fibrils formed by the 40-residue beta-amyloid peptide associated with Alzheimer's… (More)
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Highly Cited
2008
Highly Cited
2008
The aggregation of proteins into amyloid fibrils is associated with several neurodegenerative diseases. In Parkinson's disease it… (More)
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Highly Cited
2008
Highly Cited
2008
Although soluble oligomeric and protofibrillar assemblies of Abeta-amyloid peptide cause synaptotoxicity and potentially… (More)
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Highly Cited
2002
Highly Cited
2002
Although extensive data support a central pathogenic role for amyloid β protein (Aβ) in Alzheimer's disease, the amyloid… (More)
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Highly Cited
2002
Highly Cited
2002
Under solution conditions where the native state is destabilized, the largely helical polypeptide hormone insulin readily… (More)
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Highly Cited
1999
Highly Cited
1999
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is thought to be caused in part by the age-related… (More)
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Highly Cited
1997
Highly Cited
1997
Tissue deposition of normally soluble proteins as insoluble amyloid fibrils is associated with serious diseases including the… (More)
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Highly Cited
1995
Highly Cited
1995
Extracellular deposition of amyloid fibrils is responsible for the pathology in the systemic amyloidoses and probably also in… (More)
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Highly Cited
1989
Highly Cited
1989
We used a fluorometric method to examine amyloid fibrils, in vitro. These fibrils in the case of both murine senile and secondary… (More)
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