Amyloid Beta Precursor Protein Measurement

Known as: APPB, Amyloid Precursor Beta, Amyloid Precursor Protein 
The determination of the amount of amyloid beta precursor protein present in a sample.
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a metabolic disease with molecular and… (More)
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Review
2012
Review
2012
Synaptic pathology and mitochondrial oxidative damage are early events in Alzheimer's disease (AD) progression. Loss of synapses… (More)
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Highly Cited
2010
Highly Cited
2010
Reactive gliosis surrounding amyloid beta (Abeta) plaques is an early feature of Alzheimer's disease pathogenesis and has been… (More)
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Review
2007
Review
2007
Autophagy is the sole pathway for organelle turnover in cells and is a vital pathway for degrading normal and aggregated proteins… (More)
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2007
2007
Major characteristics of Alzheimer's disease (AD) are synaptic loss, cholinergic dysfunction, and abnormal protein depositions in… (More)
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Highly Cited
2003
Highly Cited
2003
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been known to reduce risk for Alzheimer's disease. In addition to the anti… (More)
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Highly Cited
2002
Highly Cited
2002
Beta-secretase cleavage represents the first step in the generation of Abeta polypeptides and initiates the amyloid cascade that… (More)
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Highly Cited
2002
Highly Cited
2002
Most Down's syndrome (DS) patients develop Alzheimer's disease (AD) neuropathology. Astrocyte and neuronal cultures derived from… (More)
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Highly Cited
2002
Highly Cited
2002
Defining the molecular mechanisms that integrate diverse signaling pathways at the level of gene transcription remains a central… (More)
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Highly Cited
2000
Highly Cited
2000
To analyze the relationship between the deposition of amyloid beta peptides (Abeta) and neuronal loss in transgenic models of… (More)
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