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Amyloid Beta A4 Precursor Protein-Binding Family A Member 2

Known as: Adapter Protein X11beta, Neuronal Munc18-1-Interacting Protein 2, Neuron-Specific X11L Protein 
Amyloid beta A4 precursor protein-binding family A member 2 (749 aa, ~83 kDa) is encoded by the human APBA2 gene. This protein plays a role in the… Expand
National Institutes of Health

Papers overview

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2017
2017
The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain… Expand
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2015
2015
Alzheimer’s disease (AD) and depression in late life are one of the most severe health problems in the world disorders. Serotonin… Expand
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Highly Cited
2013
Highly Cited
2013
Late-onset Alzheimer’s disease (LOAD) risk is strongly influenced by genetic factors such as the presence of the apolipoprotein E… Expand
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2012
2012
Overexpression of neuronal adaptor protein X11&bgr; has been shown to decrease the production of amyloid-&bgr;, a toxic peptide… Expand
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2009
2009
We recently reported an autistic proband and affected sibling with maternally inherited microduplications within the 15q13.1 and… Expand
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2007
2007
Treatment of neurons with okadaic acid, a protein phosphatase-2A inhibitor, has been used to induce tau phosphorylation and… Expand
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Highly Cited
2003
Highly Cited
2003
Previously we found that X11-like protein (X11L) associates with amyloid β-protein precursor (APP). X11L stabilizes APP… Expand
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2003
2003
BackgroundChromosomal abnormalities affecting human chromosome 15q11-q13 underlie multiple genomic disorders caused by deletion… Expand
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2000
2000
We isolated a cDNA encoding a novel protein, XB51, that interacts with the amino-terminal domain of the neuron-specific X11-like… Expand
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2000
2000
It is widely believed that one of the causes of Alzheimer's disease (AD) is the generation and secretion of beta-amyloid (Abeta… Expand
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