Amphiregulin

Known as: AMR, Schwannoma derived Growth Factor, Colorectum Cell-Derived Growth Factor 
An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
0204019862018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Autocrine, paracrine, and juxtacrine are recognized modes of action for mammalian EGFR ligands including EGF, TGF-α (TGF… (More)
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Highly Cited
2009
Highly Cited
2009
The Hippo signalling pathway regulates cellular proliferation and survival, thus has profound effects on normal cell fate and… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To study the power of the epidermal growth factor receptor (EGFR) epiregulin (EREG) and amphiregulin (AREG) ligands… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE The antiepidermal growth factor receptor (EGFR) antibody cetuximab shows activity in multiple epithelial tumor types… (More)
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Highly Cited
2007
Highly Cited
2007
Most mammary gland development occurs after birth under the control of systemic hormones. Estrogens induce mammary epithelial… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS Chronic inflammation is a risk factor for colon cancer in patients with ulcerative colitis (UC). The molecular… (More)
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Highly Cited
2005
Highly Cited
2005
Epithelial-mesenchymal crosstalk is essential for tissue morphogenesis, but incompletely understood. Postnatal mammary gland… (More)
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2005
2005
Clinically, the Fas and Fas ligand system plays a central role in the development of hepatocyte apoptosis, a process contributing… (More)
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2005
2005
BACKGROUND AND AIMS Liver regeneration is a unique response directed to restore liver mass after resection or injury. The… (More)
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Highly Cited
1989
Highly Cited
1989
The complete amino acid sequence of amphiregulin, a bifunctional cell growth modulator, was determined. The truncated form… (More)
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