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Significance Mammalian barrier surfaces are exposed to environmental stimuli that can result in tissue damage. Interleukin (IL… Expand Autocrine, paracrine, and juxtacrine are recognized modes of action for mammalian EGFR ligands including EGF, TGF-α (TGF… Expand Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary… Expand The Hippo signalling pathway regulates cellular proliferation and survival, thus has profound effects on normal cell fate and… Expand PURPOSE
The antiepidermal growth factor receptor (EGFR) antibody cetuximab shows activity in multiple epithelial tumor types… Expand The molecular bridges that link the LH surge with functional changes in cumulus cells that possess few LH receptors are being… Expand Epithelial-mesenchymal crosstalk is essential for tissue morphogenesis, but incompletely understood. Postnatal mammary gland… Expand Cells dividing at the time of carcinogen exposure are at particular risk for neoplasia. Tobacco smoke contains numerous… Expand WT1 encodes a zinc finger transcription factor implicated in kidney differentiation and tumorigenesis. In reporter assays, WT1… Expand DURING the development of the nervous system, cells require growth factors that regulate their division and survival. To identify… Expand