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Aminooxyacetic Acid

Known as: Acid, Aminooxyacetic, Aminooxyacetic Acid [Chemical/Ingredient], Acetic acid, (aminooxy)- 
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (2)

Aminooxyacetatebenzaldoxime-oxyacetic acid

Broader (2)

Enzyme InhibitorsGABA Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1986
Highly Cited
1986
The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells.
Highly Cited
1985
Highly Cited
1985
GABAergic drugs and sexual behaviour in the male rat.
1984
1984
Relationship between drug-induced increases of GABA levels in discrete brain areas and different pharmacological effects in rats.
Highly Cited
1982
Highly Cited
1982
Comparative assay of anticonvulsant and toxic potencies of sixteen GABAmimetic drugs
Highly Cited
1982
Highly Cited
1982
The Use of Inhibitors of GABA‐Transaminase for the Determination of GABA Turnover in Mouse Brain Regions: An Evaluation of Aminooxyacetic Acid and Gabaculine
Abstract: The accumulation of γ‐aminobutyric acid (GABA) after inhibition of GABA‐T (4‐aminobutyrate: 2‐oxoglutamate… 
Highly Cited
1980
Highly Cited
1980
A Gerbil Model of Cerebral Ischemia Suitable for Drug Evaluation
Cerebral ischemia was produced in the Mongolian gerbil by bilateral occlusion of the carotid arteries. Although the cerebral… 
Highly Cited
1980
Highly Cited
1980
Benzodiazepines modulate striatal enkephalin levels via a GABAergic mechanism.
Highly Cited
1979
Highly Cited
1979
IN VIVO RELEASE OF ENDOGENOUS GABA FROM RAT SUBSTANTIA NIGRA MEASURED BY A NOVEL METHOD
A sensitive GABA assay using HPLC coupled with fluorimetric detection with o‐phthalaldehyde is described. GABA, lysine and… 
Highly Cited
1978
Highly Cited
1978
GABA and gonadal hormones
Highly Cited
1978
Highly Cited
1978
Aminooxyacetic acid induced changes in gamma-aminobutyrate metabolism at the subcellular level.
Aminooxyacetic acid (AOAA) (0.1 or 0.23 mmol/kg) was administered to mice which were killed 1.5 and 6 h after treatment… 
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