Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Amino Acid Substitution

Known as: Amino Acid Substitutions, Substitution, Amino Acid, Substitutions, Amino Acid 
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Toxoplasma gondii (T. gondii) is a global protozoan parasite infecting up to one-third of the world population. Pyrimethamine… Expand
Is this relevant?
Highly Cited
2015
Highly Cited
2015
UNLABELLED We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions… Expand
Is this relevant?
Highly Cited
2012
Highly Cited
2012
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2012
Highly Cited
2012
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on protein function. It was first… Expand
  • table 1
  • figure 1
  • figure 1
  • table 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding… Expand
  • figure 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Many missense substitutions are identified in single nucleotide polymorphism (SNP) data and large-scale random mutagenesis… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The removal or repair of DNA damage has a key role in protecting the genome of the cell from the insults of cancer-causing agents… Expand
  • table 2
  • table 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved for the alignment… Expand
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Methods for alignment of protein sequences typically measure similarity by using a substitution matrix with scores for all… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?