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Amino Acid Substitution

Known as: Amino Acid Substitutions, Substitution, Amino Acid, Substitutions, Amino Acid 
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent… 
National Institutes of Health

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Related topics

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Missense MutationMutagenesis, Site-Directedaspects of radiation effectsphysiological aspects

Papers overview

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2008
2008
Amino acid substitution in the coat protein of Melon necrotic spot virus causes loss of binding to the surface of Olpidium bornovanus zoospores
Melon necrotic spot virus (MNSV) is transmitted by the fungus Olpidiumbornovanus. In this study, we used immunofluorescence… 
1993
1993
Mutations of the human cytomegalovirus immediate-early 2 protein defines regions and amino acid motifs important in transactivation of transcription from the HIV-1 LTR promoter.
The human cytomegalovirus (HCMV) immediate-early two (IE2) protein of 579 amino acids significantly activates expression from the… 
1991
1991
Phospholipase C-delta gene of the spontaneously hypertensive rat harbors point mutations causing amino acid substitutions in a catalytic domain.
This study was undertaken in order to investigate the newly discovered spontaneously hypertensive rat (SHR)-specific restriction… 
Highly Cited
1986
Highly Cited
1986
Sequence analysis of the P and C protein genes of human parainfluenza virus type 3: patterns of amino acid sequence homology among paramyxovirus proteins.
The complete nucleotide sequence of the P + C mRNA of human parainfluenza virus type 3 (PF3) was determined by sequencing cDNA… 
1986
1986
Effect of amino acid substitutions at the signal peptide cleavage site of the Escherichia coli major outer membrane lipoprotein.
The requirement for the glycine residue at the COOH terminus of the signal peptide of the precursor of the major Escherichia coli… 
1984
1984
Local effects of amino acid substitutions on the active site region of lysozyme: a comparison of physical and immunological results.
Differences in the binding of the substrate analogue chitotriose to lysozymes correlate with amino acid substitutions in the… 
1980
1980
Amino acid substitutions in protein biosynthesis. Poly(A)-directed polyphenylalanine synthesis.
The fidelity of protein biosynthesis in vitro was studied quantitatively in a well defined system that employed poly(A) as a… 
Highly Cited
1979
Highly Cited
1979
Isolation and characterization of the histone variants in chicken erythrocytes.
Chicken erythrocyte histones 2A, 2B, and 3 can be resolved into nonallelic primary structure variants by polyacrylamide gel… 
Highly Cited
1970
Highly Cited
1970
Immunological activity of cytochrome c. I. Precipitating antibodies to monomeric vertebrate cytochromes c.
Abstract The production of antibodies by rabbits in response to monomeric preparations of human, Macaca mulatta, and horse… 
Highly Cited
1968
Highly Cited
1968
Genetic and Enzymatic Experiments Relating to the Tertiary Structure of β-Galactosidase
Fifty-six amber mutations of the β-galactosidase gene of Escherichia coli were suppressed by crossing into a stock containing the…