Alzheimer's Disease Pathway KEGG

Known as: Alzheimer's Disease 
Alzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Alzheimer's disease (AD) is associated with neurodegeneration in vulnerable limbic and heteromodal regions of the cerebral cortex… (More)
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Highly Cited
2006
Highly Cited
2006
Mitochondrial dysfunction is one of the major intracellular lesions of Alzheimer's disease (AD). However, the causative factors… (More)
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Review
2005
Review
2005
From Alois Alzheimer's description of Auguste D.'s brain in 1907 to George Glenner's biochemical dissection of beta-amyloid in… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies have suggested that neuronal death in Alzheimer's disease or ischemia could arise from dysfunction of the… (More)
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Highly Cited
2003
Highly Cited
2003
The neuropathological correlates of Alzheimer's disease (AD) include amyloid-beta (Abeta) plaques and neurofibrillary tangles. To… (More)
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Highly Cited
1999
Highly Cited
1999
Mutations in the gene encoding the amyloid protein precursor (APP) cause autosomal dominant Alzheimer's disease. Cleavage of APP… (More)
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Highly Cited
1998
Highly Cited
1998
Abeta1-42 is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer's pathogenesis… (More)
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Highly Cited
1998
Highly Cited
1998
Genetic causes of Alzheimer's disease (AD) include mutations in the amyloid precursor protein (APP), presenilin 1 (PS1), and… (More)
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Highly Cited
1991
Highly Cited
1991
Alzheimer's disease is a form of localized amyloidosis characterized by cerebral cortical amyloid plaques, neurofibrillary… (More)
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Highly Cited
1990
Highly Cited
1990
An amyloid protein that precipitates in the cerebral vessel walls of Dutch patients with hereditary cerebral hemorrhage with… (More)
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