Alpha-Amanitin

Known as: Alpha Amanitine, Alpha Amanitin, Alpha-Amanitine 
A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
02419692017

Papers overview

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2011
2011
  • 2011
Between August 8, 1974, and November 1, 1978, calls reporting 100 cases of mushroom poisoning were received by the National… (More)
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2004
2004
Our laboratory has developed methods for transient state kinetic analysis of human RNA polymerase II elongation. In these studies… (More)
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Highly Cited
1996
Highly Cited
1996
Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide… (More)
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1991
1991
Transcription of the predominant surface antigen genes in Trypanosoma brucei is unusual in its resistance to the RNA polymerase… (More)
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1989
1989
The variant cell surface glycoprotein (VSG) gene expression sites of the protozoan Trypanosoma brucei are transcribed by an… (More)
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1984
1984
Many, if not all, mRNAs in T.brucei start with the same sequence of 35 nucleotides, separately encoded in clustered so-called… (More)
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1982
1982
Three wild strains of D. melanogaster have been identified which are resistant to normally lethal levels of the fungal toxin… (More)
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1979
1979
Following EMS mutagenesis we recovered a mutant of D. melanogaster that grows at concentrations of alpha-amanitin lethal to wild… (More)
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1976
1976
A number of mutant Chinese hamster ovary (CHO) cell lines resistant to the cytotoxic action of alpha-amanitin have been isolated… (More)
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1969
1969
Evidence has been presented that a amanitin, the potent bicyclic polypeptide toxin of the toad­ stool amanita phalloides inhibits… (More)
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