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Allogeneic Natural Killer Cell Line NK-92

Known as: NK-92, NK-92 Cells 
A proprietary, human cytotoxic cell line composed of allogeneic, activated, interleukin-2 (IL-2) dependent-natural killer cells derived from a 50… 
National Institutes of Health

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NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Sestrin 2 and sestrin 3 suppress NK-92 cell-mediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC 1 signaling
Ovarian cancer is one of the major cancer types. NK-92 cell line, which has consistently and reproducibly high anti-tumor… 
2017
2017
Abstract P2-04-17: Directing NK cells to Trop-2-expressing breast and other cancers, with chimeric antigen receptors
Adoptive immunotherapy with chimeric antigen receptor (CAR)-engineered T or NK cells is in active clinical and preclinical… 
2015
2015
In Vitro and In Vivo Comparison of Lymphocytes Transduced with a Human CD 16 or with a Chimeric Antigen Receptor Reveals Potential Off-Target Interactions due to the IgG 2 CH 2CH 3 CAR-Spacer
The present work was designed to compare two mechanisms of cellular recognition based on Ab specificity: firstly, when the… 
Review
2013
Review
2013
NK-92 Cytotoxicity Against Cancer Stem Cells in Hematologic Malignancies
The discovery that many cancers are driven by a rare population of cancer stem cells has raised new questions as to how the… 
2009
2009
Transfection of NK Cells with mRNA or Lentivirus Expressing Chimeric Antigen Receptors Results in Highly Efficient Killing of Lymphoid Malignancies and Compares Favorably with Monoclonal Antibody…
Abstract 1696 Poster Board I-722 NK cells frequently do not kill malignant lymphoid target cells except through antibody… 
2007
2007
Proteomic analysis of human NK-92 cells after NK cell-mediated cytotoxicity against K562 cells
To better understand the natural killer (NK) cell cytotoxicity mechanism at the proteome level, we comparatively analyzed the… 
2007
2007
RAET 1 E 2 , a Soluble Isoform of the UL 16-binding Protein RAET 1 E Produced by Tumor Cells , Inhibits NKG 2 D-mediated NK Cytotoxicity *
UL16-binding proteins (ULBPs, also termed as retinoic acid early transcripts, encoded by RAET1 genes), a family of ligands for… 
2005
2005
AKT plays a role in the survival of the tumor cells of extranodal NK/T-cell lymphoma, nasal type.
Phosphorylated AKT has been detected in extranodal NK/T-cell lymphoma, nasal type (ENTL). Either interleukin-2 (IL-2) or… 
2003
2003
The Characterization of NK-92 Cell Line Transfected with Human Stem Cell Factor Gene
Objective: To study the characterization of NK cell line transfected with hSCF gene.Methods: pcDNA3 hSCF was transfected into NK… 
1997
1997
Mechanism of leukemic cell killing by IL-2 activated natural killer cells : role of cell adhesion molecules
Natural killer (NK) cells and lymphokine activated NK (LAK) cells, contribute to the elimination and growth control of malignant… 
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