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AlloSteric Database

Known as: ASD 
Allostery is the most direct and efficient way for regulation of biological macromolecule function induced by the binding of a ligand at an… 
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Papers overview

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2018
2018
Microorganisms recognize and respond to harmful external environments by producing defense proteins, the expression of which is… 
2016
2016
s | 3 of adverse effects that currently limit the use of opioids in the clinic. Supported by USPHS Grant K05DA017918 PM288… 
2010
2010
The present invention provides a compound of formula (I) The present invention also provides a pharmaceutical composition, the… 
2008
2008
FFA2 (GPR43) has been identified as a receptor for short-chain fatty acids (SCFAs) that include acetate and propionate. FFA2 is… 
2008
2008
Allosteric cooperativity in inhibition of protein kinase A was studied for the first time kinetically, by using the second-order… 
2005
2005
3α-reduced neuroactive steroids such as 3α, 5α-tetrahydroprogesterone (3α, 5α-THP) and 3α, 5α-tetrahydrodeoxycorticosterone (3… 
2001
2001
血管新生は、血管新生の増加が望ましい状態の治療に望ましい位置で血管新生を誘導するのに有効な量の選択的アデノシンA 1 アロステリックエンハンサーを投与することによって処理され、当該状態としては、例えば卒中、心疾患、および末梢血管疾患がある。 選択的アデノシンA 1 アロステリックエンハンサーは、血管新生の減少が望ましい状態の治療に望ましい位置で血管新生を阻害するのに有効な量で投与され、当該状態としては、例えば腫瘍、糖尿病性網膜症、リウマチ様関接炎や乾癬のような炎症性疾患がある。 
2001
2001
Pharmaceutical agents that may be protective to the heart during ischemia were targeted in this project. Analogs to a lead… 
Highly Cited
1997
Highly Cited
1997
The γ-aminobutyric acidA (GABA) receptor in the mammalian central nervous system is composed of pentameric combinations of α1–6…