Allelic Imbalance

Known as: Allelic Imbalances, Allele Imbalance, Imbalance, Allelic 
Any variance from the expected 1:1 ratio for the expression of the two inherited parental alleles for the same gene.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Complex human traits are influenced by variation in regulatory DNA through mechanisms that are not fully understood. Because… (More)
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Highly Cited
2012
Highly Cited
2012
UNLABELLED DNA repair competency is one determinant of sensitivity to certain chemotherapy drugs, such as cisplatin. Cancer cells… (More)
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Highly Cited
2005
Highly Cited
2005
During the evolution of cancer, the incipient tumour experiences ‘oncogenic stress’, which evokes a counter-response to eliminate… (More)
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Highly Cited
2005
Highly Cited
2005
We have developed a robust algorithm for copy number analysis of the human genome using high-density oligonucleotide microarrays… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Allelic imbalance (AI), the loss or gain of chromosomal regions, is found in many cancers. AI can be detected in… (More)
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2002
2002
Bilateral breast cancer (biBC) is a common form of breast cancer; however, it has not been subjected to systematic comparative… (More)
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2001
2001
BACKGROUND & AIMS Cirrhotic nodules have long been assumed to be the precancerous lesions of hepatocellular carcinoma (HCC). We… (More)
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2000
2000
The PTEN/MMAC1/TEP1 tumor-suppressor gene, which maps to chromosome 10q23.3, is mutated and homozygously deleted in a variety of… (More)
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2000
2000
BACKGROUND Few studies have addressed in detail the genetic alterations that occur in vulvar squamous carcinomas (VSCC) and their… (More)
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Highly Cited
1996
Highly Cited
1996
Although prostate cancer is one of the most common malignancies of males in Western countries, relatively little is known about… (More)
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