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Allelic Imbalance

Known as: Allelic Imbalances, Allele Imbalance, Imbalance, Allelic 
Any variance from the expected 1:1 ratio for the expression of the two inherited parental alleles for the same gene.
National Institutes of Health

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aspects of radiation effectsphysiological aspects

Papers overview

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2013
2013
Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myctransgenic mice that contain a germline amplicon of tumor-promoting genes
The DNA damage response (DDR) can restrain the ability of oncogenes to cause genomic instability and drive malignant… 
2013
2013
Molecular characteristics of meningiomas in a cohort of Indian patients: loss of heterozygosity analysis of chromosomes 22, 17, 14 and 10.
BACKGROUND Though, loss of heterozygosity (LOH) at chromosome 22q is considered to be the most likely initiating event in the… 
2007
2007
CNAT 4 . 0 : Copy Number and Loss of Heterozygosity Estimation Algorithms for the GeneChip ® Human Mapping 10 / 50 / 100 / 250 / 500 K Array Set
  • 2007
  • Corpus ID: 17112743
Introduction There exists evidence of correlations between carcinogenesis and genetic alterations in tumor cells. These… 
2006
2006
A Lethal Change in the Weather: Temperature Extremes and Premature Mortality
in the sample population ranged from 31% to 92% (mean 68%). Two regions of the chromosome arm showed Al values greater than the… 
2003
2003
Allelic imbalance at intragenic markers of Tbx18 is a hallmark of murine osteosarcoma.
We have recently identified a locus exhibiting a high frequency of allelic imbalance (AI) in both spontaneous human (HSA 6q14.1… 
2002
2002
Analysis of Neuroblastoma Novel Regions of Allelic Imbalance Identified by Genome-wide Updated Version
Several nonrandom chromosomal abnormalities have been associated with neuroblastoma (NB). However, the relationship of each… 
2001
2001
Analysis of Allelic Imbalance in Patients With Colorectal Cancer According to Stage and Presence of Synchronous Liver Metastases
ObjectiveTo investigate the relationship between number and location of allelic imbalances (AI) and local tumor progression… 
2001
2001
Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non‐small cell lung carcinomas (NSCLCs)
The FHIT gene, located at the FRA3B fragile site of chromosome 3p14.2, encodes a 16.8 kD homologue of the yeast enzyme… 
1999
1999
Prognostic significance of allelic imbalances on chromosome 9p in stage I non-small cell lung carcinoma.
Loss of heterozygosity (LOH) on chromosomes 2q, 9p, 18q, and 22q frequently occurs in advanced non-small cell lung carcinoma… 
1995
1995
Allele losses on chromosome 17 in ovarian tumours
Analysis of tumours for localized loss of heterozygosity (LOH) or ‘allele imbalance’ is a well-recognized approach to the… 
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