Allele-Specific Oligonucleotide

Known as: ASO 
An oligonucleotide designed to be specific for only one allele of a gene.
National Institutes of Health

Papers overview

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2014
2014
Detection of MYD88 L265P mutation by real-time allele-specific oligonucleotide polymerase chain reaction.
MYD88 L265P mutation has been reported in ∼90% of Waldenström's Macroglobulinemia (WM) patients and immunoglobulin M (IgM… (More)
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2012
2012
Analysis of common mitochondrial DNA mutations by allele-specific oligonucleotide and Southern blot hybridization.
Mitochondrial disorders are clinically and genetically heterogeneous. There are a set of recurrent point mutations in the… (More)
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2000
2000
DNA damage promotes mistyping in the allele specific oligonucleotide probing analysis of forensic samples.
Five polymerase chain reaction (PCR) products which could not be reliably typed by allele-specific oligonucleotide (ASO) probing… (More)
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Review
2000
Review
2000
High-throughput genotyping assay approaches.
High-throughput genotyping approaches are being developed to meet the demands of pharmacogenomnics, where numerous individuals… (More)
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2000
2000
The allele frequency of mutations in four genes that confer enhanced susceptibility to venous thromboembolism in an unselected group of New York State newborns.
The frequencies of Factor V G1691A (FVL), prothrombin (PT) G20210A, 5'10'methylenetetrahydrofolate reductase (MTHFR) C677T, and… (More)
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1999
1999
The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks.
Gs alpha mutations and histopathology have been analysed in a series of 13 patients with fibrous dysplasia (FD) of bone… (More)
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1999
1999
Rapid detection of CYP1A1, CYP2D6, and NAT variants by multiplex polymerase chain reaction and allele-specific oligonucleotide assay.
Drugs and carcinogens are excreted from the body after metabolic conversion involving enzymes mediating oxidative metabolism and… (More)
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1994
1994
Rapid determination of platelet alloantigen genotypes by polymerase chain reaction using allele-specific primers.
BACKGROUND The technique of allele-specific polymerase chain reaction (PCR) amplification has been adapted for DNA-based human… (More)
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1992
1992
HLA-DQB1 genotype in Sardinian multiple sclerosis: evidence for a key role of DQB1 *0201 and *0302 alleles.
We studied HLA-DQB1 haplotypes in 103 unrelated multiple sclerosis (UMS) patients and in 26 related (RMS) patients from 12… (More)
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1991
1991
Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligonucleotide probes.
The prediction of neonatal alloimmune thrombocytopenia (NATP) in affected families has, in the past, been based on information… (More)
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