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Allele-Specific Oligonucleotide

Known as: ASO 
An oligonucleotide designed to be specific for only one allele of a gene.
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
The detection of minimal residual disease (MRD) using immunoglobulin and T-cell receptor (TCR) rearrangements as PCR targets… Expand
Highly Cited
1999
Highly Cited
1999
Gsα mutations and histopathology have been analysed in a series of 13 patients with fibrous dysplasia (FD) of bone, including 12… Expand
Highly Cited
1999
Highly Cited
1999
Drugs and carcinogens are excreted from the body after metabolic conversion involving enzymes mediating oxidative metabolism and… Expand
Highly Cited
1999
Highly Cited
1999
CONTEXT Infertile men with obstructive azoospermia may have mutations in the cystic fibrosis transmembrane conductance regulator… Expand
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Highly Cited
1997
Highly Cited
1997
Mitochondrial defects can be caused by mutations in nuclear or mitochondrial DNA. Large deletion/duplication and point mutations… Expand
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Highly Cited
1995
Highly Cited
1995
Isolation of the gene for cystic fibrosis (CF), the cystic fibrosis transmembrane conductance regulator (CFTR), provided a basis… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND: The technique of allele‐specific polymerase chain reaction (PCR) amplification has been adapted for DNA‐based human… Expand
Review
1993
Review
1993
  • R. Cotton
  • Mutation research
  • 1993
  • Corpus ID: 39572014
Mutation detection is important in all areas of biology. Detection of unknown mutations can involve sequencing of kilobases of… Expand
Highly Cited
1991
Highly Cited
1991
The prediction of neonatal alloimmune thrombocytopenia (NATP) in affected families has, in the past, been based on information… Expand
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Highly Cited
1989
Highly Cited
1989
A membrane-bound cytochrome b, a heterodimer formed by a 91-kD glycoprotein and a 22-kD polypeptide, is a critical component of… Expand
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