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Allele-Specific Oligonucleotide

Known as: ASO 
An oligonucleotide designed to be specific for only one allele of a gene.
National Institutes of Health

Papers overview

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2012
2012
Analysis of common mitochondrial DNA mutations by allele-specific oligonucleotide and Southern blot hybridization.
Mitochondrial disorders are clinically and genetically heterogeneous. There are a set of recurrent point mutations in the… 
2003
2003
ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish.
2000
2000
DNA damage promotes mistyping in the allele specific oligonucleotide probing analysis of forensic samples
Five polymerase chain reaction (PCR) products which could not be reliably typed by allele‐specific oligonucleotide (ASO) probing… 
2000
2000
Fluorescent oligonucleotide ligation technology for identification of ras oncogene mutations
A mutation detection strategy based on multiplex PCR followed by multiplex allele-specific oligonucleotide probe ligation was… 
Highly Cited
1997
Highly Cited
1997
Direct detection of multiple point mutations in mitochondrial DNA.
Mitochondrial defects can be caused by mutations in nuclear or mitochondrial DNA. Large deletion/duplication and point mutations… 
1994
1994
Major Histocompatibility Complex Class‐II Alleles in Primary Biliary Cirrhosis
The major histocompatibility complex (MHC) class‐II alleles at the DRBI, DQBl and DPBl loci were investigated in 40 patients with… 
1994
1994
DNA polymorphisms of human apolipoprotein A‐IV gene: frequency and effects on lipid, lipoprotein and apolipoprotein levels in a French population
Genetic polymorphisms of apolipoprotein (apo) A‐IV have been shown to influence lipoprotein metabolism in some human populations… 
1993
1993
Single-step allele-specific polymerase chain reaction HLA-DQ genotyping using ARMS primers.
Highly Cited
1990
Highly Cited
1990
Two novel variants of transthyretin identified in Japanese cases with familial amyloidotic polyneuropathy: transthyretin (Glu42 to Gly) and transthyretin (Ser50 to Arg).
Highly Cited
1989
Highly Cited
1989
A novel ochre mutation in the beta-thalassemia gene of a Thai. Identification by direct cloning of the entire beta-globin gene amplified using polymerase chain reactions.
The beta-globin genes from a Thai patient compound heterozygous for beta-thalassemia and HbE disease were investigated. The 3.0… 
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