Alkaline phosphatase isoenzyme, bone fraction

Known as: BSAP, bALP, alkaline phosphatase bone 
An isoform of alkaline phosphatase found on the surface of osteoblasts. The level of this enzyme in a patient's serum is proportional to the amount… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2017
05010015019622017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sclerostin, an osteocyte-secreted protein, negatively regulates osteoblasts and inhibits bone formation. In this first-in-human… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT The optimal duration of treatment of women with postmenopausal osteoporosis is uncertain. OBJECTIVE To compare the… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Three large, randomized trials of patients with bone metastases recently demonstrated that zoledronic acid reduces the… (More)
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Highly Cited
2004
Highly Cited
2004
UNLABELLED The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to… (More)
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Highly Cited
2003
Highly Cited
2003
Studies in rodents have implicated various cytokines as paracrine mediators of increased osteoclastogenesis during estrogen… (More)
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Highly Cited
2000
Highly Cited
2000
The mechanisms leading to increased bone loss and skeletal fragility in women with postmenopausal osteoporosis are still poorly… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVES To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN… (More)
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Highly Cited
1996
Highly Cited
1996
Changes of bone turnover with aging are responsible for bone loss and play a major role in osteoporosis. Although an increase of… (More)
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Highly Cited
1996
Highly Cited
1996
Acquired hypogonadism is being increasingly recognized in adult men. However, the effects of long term testosterone replacement… (More)
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Highly Cited
1994
Highly Cited
1994
To evaluate the clinical utility of recently developed biochemical markers of bone turnover to monitor the response of… (More)
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