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Alkaline phosphatase isoenzyme, bone fraction

Known as: BSAP, bALP, alkaline phosphatase bone 
An isoform of alkaline phosphatase found on the surface of osteoblasts. The level of this enzyme in a patient's serum is proportional to the amount… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sclerostin, an osteocyte‐secreted protein, negatively regulates osteoblasts and inhibits bone formation. In this first‐in‐human… 
Highly Cited
2006
Highly Cited
2006
CONTEXT The optimal duration of treatment of women with postmenopausal osteoporosis is uncertain. OBJECTIVE To compare the… 
Highly Cited
2004
Highly Cited
2004
The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to RANKL, was… 
Highly Cited
2003
Highly Cited
2003
Studies in rodents have implicated various cytokines as paracrine mediators of increased osteoclastogenesis during estrogen… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain… 
Highly Cited
2000
Highly Cited
2000
The mechanisms leading to increased bone loss and skeletal fragility in women with postmenopausal osteoporosis are still poorly… 
Highly Cited
2000
Highly Cited
2000
BACKGROUND No published studies have directly examined the effect of soy protein with isoflavones on bone or bone turnover in… 
Highly Cited
1996
Highly Cited
1996
Changes of bone turnover with aging are responsible for bone loss and play a major role in osteoporosis. Although an increase of… 
Highly Cited
1996
Highly Cited
1996
Acquired hypogonadism is being increasingly recognized in adult men. However, the effects of long term testosterone replacement… 
Highly Cited
1994
Highly Cited
1994
To evaluate the clinical utility of recently developed biochemical markers of bone turnover to monitor the response of…