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Alfentanil

Known as: Alfentanil [Chemical/Ingredient], Alfentanilum, N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide 
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (2)

AlfentaR-39209
Alfentanil hydrochlorideAlfentanil:MCnc:Pt:Ser/Plas:QnAlfentanil:Mass:Pt:Dose:QnAlfentanil:PrThr:Pt:Urine:Ord

Broader (3)

Analgesics, OpioidAnesthetics, IntravenousNarcotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
The laryngeal mask airway for awake craniotomy in the pediatric patient: report of three cases.
Highly Cited
2003
Highly Cited
2003
Pharmacological modulation of experimental phasic and tonic muscle pain by morphine, alfentanil and ketamine in healthy volunteers
Background:  Muscle pain is a major clinical problem but the underlying mechanisms and its pharmacological modulation need… 
Highly Cited
1998
Highly Cited
1998
Esmolol Potentiates Reduction of Minimum Alveolar Isoflurane Concentration by Alfentanil
Esmolol, a short-acting beta1-receptor antagonist, decreases anesthetic requirements during propofol/N2 O/morphine anesthesia… 
Highly Cited
1996
Highly Cited
1996
Time Course Characteristics of Acute Tolerance Development to Continuously Infused Alfentanil in Rats
The time course of the development of acute tolerance to alfentanil was characterized in rat experiments using various algorithms… 
Highly Cited
1991
Highly Cited
1991
Alfentanil infusion for postoperative pain: a comparison of epidural and intravenous routes.
The efficacy of intravenous (iv) and epidural infusions of alfentanil for postoperative pain relief was investigated in 24… 
Highly Cited
1990
Highly Cited
1990
Alfentanil Potentiates Midazolam‐Induced Unconsciousness in Subanalgesic Doses
The effects of alfentanil on the midazolam dose-response curve for hypnosis was studied with response to the verbal command as an… 
Highly Cited
1989
Highly Cited
1989
Sufentanil, Alfentanil, and Fentanyl: Impact on Cerebrospinal Fluid Pressure in Patients with Brain Tumors
Summary In order to evaluate the safety of the new synthetic opioids, alfentanil and sufentanil, in neurosurgical patients, we… 
Highly Cited
1984
Highly Cited
1984
Optimization of the radioimmunoassays for measuring fentanyl and alfentanil in human serum.
Measurement of serum fentanyl and alfentanil concentrations by radioimmunoassay (RIA) may result in significant errors and high… 
Highly Cited
1983
Highly Cited
1983
Catecholamine and cortisol responses to sufentanil-O2 and alfentanil-O2 anaesthesia during coronary artery surgery
The effects of alfentanil-O2 and sufentanil-O2 anaesthesia on plasma catecholamines and cortisol were investigated in 32 patients… 
1980
1980
Human volunteer studies of Alfentanyl (R39209), a new short‐acting narcotic analgesic
Alfentanyl is a new narcotic analgesic with a rapid onset and very short duration of effect, and a potency about one third of… 
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