Aldehyde dehydrogenase (NAD+)

Known as: Dehydrogenase, Aldehyde, Aldehyde NAD Oxidoreductase, D Glucuronolactone Dehydrogenase 
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
There is substantial interest in the development of drugs that limit the extent of ischemia-induced cardiac damage caused by… (More)
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Review
2007
Review
2007
The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Both… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies suggest that mitochondrial aldehyde dehydrogenase (ALDH-2) plays a central role in the process of nitroglycerin… (More)
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Review
2003
Review
2003
Aldehyde dehydrogenases catalyze the pyridine nucleotide-dependent oxidation of aldehydes to acids. Seventeen enzymes are… (More)
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Highly Cited
2003
Highly Cited
2003
The 2-oxoaldehyde methylglyoxal (MeG) is the precursor to a number of the known advanced glycation endproducts (AGE) implicated… (More)
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Highly Cited
2003
Highly Cited
2003
The aldehyde dehydrogenase (ALDH) superfamily represents a divergently related group of enzymes that metabolize a wide variety of… (More)
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Highly Cited
2003
Highly Cited
2003
In plants, oxidative stress is one of the major causes of damage as a result of various environmental stresses. Oxidative stress… (More)
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Review
1998
Review
1998
Twelve aldehyde dehydrogenase (ALDH) genes have been identified in humans. These genes, located on different chromosomes, encode… (More)
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Highly Cited
1984
Highly Cited
1984
A cyclophosphamide-resistant L1210 cell line has been shown to have unusually high aldehyde dehydrogenase activity. The… (More)
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Highly Cited
1984
Highly Cited
1984
Usual human livers contain two major aldehyde dehydrogenase [(ALDH) aldehyde:NAD+ oxidoreductase] isozymes--i.e., a cytosolic… (More)
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