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The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Both… Expand Alcohol dehydrogenase (ADH) and mitochondrial aldehyde dehydrogenase (ALDH2) are responsible for metabolizing the bulk of ethanol… Expand Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an… Expand We analyzed sequence variation for chalcone synthase (Chs) and alcohol dehydrogenase (Adh) loci in 28 species in the genera… Expand An expression system for Saccharomyces cerevisiae (Sc) has been developed which, depending on the chosen vector, allows the… Expand The liver enzymes alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are responsible for the oxidative… Expand PROTEINS often differ in amino-acid sequence across species. This difference has evolved by the accumulation of neutral mutations… Expand The neutral theory of molecular evolution predicts that regions of the genome that evolve at high rates, as revealed by… Expand It is now widely accepted that the various pharmacologic and addictive consequences of alcohol consumption are related to the… Expand Some statistical properties of samples of DNA sequences are studied under an infinite-site neutral model with recombination. The… Expand