Ag 3340

Known as: Ag-3340, Ag3340, Prinomastat/AG 3340 
 

Topic mentions per year

Topic mentions per year

1997-2013
0246819972013

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Broad-spectrum matrix metalloproteinase (MMP) inhibitors (MMPI) were unsuccessful in cancer clinical trials, partly due to side… (More)
Is this relevant?
2008
2008
Hypoxia-ischemia (H-I) can produce widespread neurodegeneration and deep cerebral white matter injury in the neonate. Resident… (More)
Is this relevant?
2007
2007
PURPOSE The efficacy of three matrix metalloproteinase (MMP) inhibitors with various selectivities (Ro-31-9790, AG3340, and DPC… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • table 2
Is this relevant?
2006
2006
BACKGROUND AND PURPOSE Cerebrovascular white matter (WM) lesions contribute to cognitive impairment and motor dysfunction in the… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
A number of different matrix metalloproteinase (MMP) inhibitors have been developed as cytostatic and anti-angiogenic agents and… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Mechanical ventilation has become an indispensable therapeutic modality for patients with respiratory failure. However, a serious… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
We studied AG3340, a potent metalloproteinase (MMP) inhibitor with pM affinities for inhibiting gelatinases (MMP-2 and -9), MT… (More)
Is this relevant?
1999
1999
Synthetic matrix metalloproteinase (MMP) inhibitors have activity against a variety of tumors in preclinical models but have not… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1999
1999
Effective therapy is needed to improve the survival of patients with advanced lung cancers. We studied the effects of a selective… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1997
1997
Matrix metalloproteinases are a family of zinc-containing proteases that degrade extracellular matrix and basement membranes… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?