Adult T-Cell Lymphoma/Leukemia

Known as: Leukemia-Lymphoma, HTLV-Associated, leukemia/lymphoma, adult T-cell, T-cell leukemia/lymphoma, adult 
A peripheral (mature) T-cell neoplasm linked to the human T-cell leukemia virus type 1 (HTLV-1). Adult T-cell leukemia/lymphoma is endemic in several… (More)
National Institutes of Health

Related topics

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Broader (1)

Acute leukemia
Atypical lymphocyteCD4 Positive T LymphocytesCommunicable DiseasesHTLV-1 Infection
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Papers overview

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Highly Cited
2012
Highly Cited
2012
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
In eukaryotes, post-translational modification of histones is critical for regulation of chromatin structure and gene expression… (More)
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Highly Cited
2010
Highly Cited
2010
Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study.
Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used as a curative option for adult T-cell leukemia… (More)
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Highly Cited
2009
Highly Cited
2009
PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients
Adult T-cell leukemia/lymphoma (ATLL) develops after infection with human T-cell leukemia virus-1 (HTLV-1) after a long latency… (More)
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Highly Cited
2004
Highly Cited
2004
Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells.
To clarify the status of tax gene, we analyzed human T-cell leukemia virus type-I (HTLV-I) associated cell lines and fresh adult… (More)
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Highly Cited
2004
Highly Cited
2004
Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells.
Adult T-cell leukaemia/lymphoma (ATLL) is an aggressive neoplastic disease that usually exhibits a CD4(+)CD25(+) phenotype… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma: its close association with skin involvement and unfavorable outcome.
Adult T-cell leukemia/lymphoma (ATLL) is a distinct clinical entity among mature T-cell neoplasms, and its causative agent has… (More)
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Highly Cited
1997
Highly Cited
1997
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.
Human T cell leukemia/lymphotropic virus type I (HTLV-I) induces adult T cell leukemia/lymphoma (ATLL). The mechanism of HTLV-I… (More)
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Review
1989
Review
1989
The biology of interleukin-6.
B CELLS ARE the only eukaryotic cells that are able to produce antibody molecules. Their growth and differentiation into antibody… (More)
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Highly Cited
1984
Highly Cited
1984
Wechsler Adult Intelligence Scale and Wechsler Adult Intelligence Scale-Revised in a neurologically impaired population.
Compared Verbal, Performance, and Full Scale IQ scores from two groups of neurologically impaired patients (N = 114) similar in… (More)
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Highly Cited
1982
Highly Cited
1982
The human type-C retrovirus, HTLV, in Blacks from the Caribbean region, and relationship to adult T-cell leukemia/lymphoma.
Type-C RNA tumor viruses have been implicated in the etiology of naturally occurring leukemias and lymphomas of animals. Human T… (More)
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