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Adrenochrome

Known as: 1H-Indole-5,6-dione, 2,3-dihydro-3-hydroxy-1-methyl-, Adrenochrome [Chemical/Ingredient] 
Pigment obtained by the oxidation of epinephrine.
National Institutes of Health

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Related topics

13 relations
In BloodProcess of secretionagonistsanalogs & derivatives
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LPD gingival message agentS-Adchnoncarbazochromeiprazochrome

Papers overview

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Highly Cited
1997
Highly Cited
1997
Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes.
o-Quinones are physiological oxidation products of catecholamines that contribute to redox cycling, toxicity and apoptosis, i.e… 
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Highly Cited
1988
Highly Cited
1988
Does captopril attenuate reperfusion‐induced myocardial dysfunction by scavenging free radicals?
The abilities of angiotensin converting-enzyme (ACE) inhibitors to suppress superoxide anion formation in vitro and to improve… 
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Highly Cited
1983
Highly Cited
1983
Enhancement of antitumor activity of ascorbate against Ehrlich ascites tumor cells by the copper:glycylglycylhistidine complex.
Ascorbate in an aqueous solution is easily oxidized by molecular oxygen in the presence of cupric ion, thus producing reactive… 
Highly Cited
1981
Highly Cited
1981
Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine: relation to pathogenesis of catecholamine cardiomyopathy.
We have examined the effects of adrenochrome and other metabolites of epinephrine on the ultrastructure and contractile activity… 
Highly Cited
1979
Highly Cited
1979
NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation.
1. Both NADH and NADPH supported the oxidation of adrenaline to adrenochrome in bovine heart submitochondrial particles. The… 
Highly Cited
1978
Highly Cited
1978
An improved spectrophotometric assay for superoxide dismutase based on epinephrine autoxidation.
Abstract Superoxide dismutase activity was assayed in terms of its ability to inhibit the radical-mediated chain-propagating… 
Highly Cited
1972
Highly Cited
1972
The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase.
Abstract The rate of autoxidation of epinephrine and the sensitivity of this autoxidation to inhibition by superoxide dismutase… 
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Highly Cited
1972
Highly Cited
1972
The univalent reduction of oxygen by reduced flavins and quinones.
Abstract FMN and flavodoxin, when reduced by the action of ferredoxin-TPN+ oxidoreductase, have been shown to cause both… 
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Review
1959
Review
1959
Metabolism of epinephrine and other sympathomimetic amines.
  • J. Axelrod
  • Physiological reviews
  • 1959
  • Corpus ID: 17683153
HE PHYSIOLOGICAL ACTIONS of epinephrine and other sympathomimetic amines are well established, yet the metabolism of these… 
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Highly Cited
1959
Highly Cited
1959
The Chemistry Of Adrenochrome And Related Compounds
s 60, 5747 (1956). (100) FRANKEL, S., AND ALLERS, R.: Biochem. Z. 18,40 (1909). (101) FRIEDENWALD, J. S., MICHEL, H., AND BUSCHKE… 
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