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Adenosine A2A Receptor Antagonist PBF-509

Known as: A2AR Antagonist PBF-509, PBF-509 
An orally bioavailable adenosine A2A receptor (A2AR) antagonist, with potential antineoplastic activity. Upon administration, A2AR antagonist PBF-509… 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Leukemia develops as the result of intrinsic features of the transformed cell, such as gene mutations and derived oncogenic… 
2018
2018
9089Background: ATP is catabolized to adenosine in the tumor microenvironment, leading to excess adenosine and immunosuppressive… 
Review
2014
Review
2014
  • A. Pinna
  • CNS Drugs
  • 2014
  • Corpus ID: 30098173
Neurotransmitters other than dopamine, such as norepinephrine, 5-hydroxytryptamine, glutamate, adenosine and acetylcholine, are…